(Q28561774)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64663

P2X7 purinoceptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64663

1 reference

17 November 2021

1 reference

17 November 2021

magnesium ion binding

1 reference

14 February 2019

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

purinergic nucleotide receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

3 references

14 February 2019

14 February 2019

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

extracellularly ATP-gated cation channel activity

An ATP-gated ion channel at the cell nucleus

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

14 February 2019

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

signaling receptor binding

1 reference

14 February 2019

Evidence for functional P2X4/P2X7 heteromeric receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

ion channel activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

1 reference

14 February 2019

copper ion binding

1 reference

14 February 2019

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

zinc ion binding

1 reference

14 February 2019

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

channel activity

1 reference

14 February 2019

P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

ATP-gated ion channel activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

scaffold protein binding

1 reference

14 February 2019

The pannexin 1 channel activates the inflammasome in neurons and astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

cell component

cytoplasm

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

14 February 2019

Coupling of two pools of P2X7 receptors to distinct intracellular signaling pathways in rat submandibular gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

Evidence for functional P2X4/P2X7 heteromeric receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

integral component of plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

1 reference

14 February 2019

membrane

2 references

bleb

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

protein-containing complex

1 reference

14 February 2019

The pannexin 1 channel activates the inflammasome in neurons and astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

neuron projection

1 reference

14 February 2019

Presence of diverse functional P2X receptors in rat cerebellar synaptic terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

terminal bouton

1 reference

14 February 2019

Presence of diverse functional P2X receptors in rat cerebellar synaptic terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

membrane raft

1 reference

14 February 2019

Coupling of two pools of P2X7 receptors to distinct intracellular signaling pathways in rat submandibular gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

postsynapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

positive regulation of protein phosphorylation

biological process

1 reference

14 February 2019

P2X7 receptors stimulate AKT phosphorylation in astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

regulation of sodium ion transport

1 reference

14 February 2019

Evidence for functional P2X4/P2X7 heteromeric receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

cation transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

cell surface receptor signaling pathway

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

organic cation transport

TAS

1 reference

14 February 2019

An ATP-gated ion channel at the cell nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

neuronal action potential

TAS

1 reference

14 February 2019

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

bleb assembly

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

ion transmembrane transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

purinergic nucleotide receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

positive regulation of cytoskeleton organization

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

membrane depolarization

1 reference

14 February 2019

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

excitatory postsynaptic potential

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

positive regulation of protein serine/threonine kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

apoptotic signaling pathway

1 reference

14 February 2019

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

cation transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64663

1 reference

14 February 2019

regulation of presynaptic dense core granule exocytosis

EXP