(Q28562058)

English

FXYD domain-containing ion transport regulator 1

mammalian protein found in Rattus norvegicus

phospholemman
sodium/potassium-transporting ATPase subunit FXYD1
Fxyd1

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Statements

1 reference

17 November 2021

Ion-transport regulator, FXYD motif, protein family

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08589

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

17 November 2021

1 reference

17 November 2021

1 reference

14 February 2019

Identification of an endogenous inhibitor of the cardiac Na+/Ca2+ exchanger, phospholemman

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

14 February 2019

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IDA

sodium channel regulator activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

14 February 2019

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IDA

ion channel regulator activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IEA

cell component

sodium:potassium-exchanging ATPase complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

14 February 2019

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

2 references

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

1 January 2018

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08589&geneProductId=UniProtKB:O08589

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IEA

potassium ion transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

1 reference

14 February 2019

FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IEP

negative regulation of protein glutathionylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

ISS

positive regulation of organic acid transport

1 reference

14 February 2019

Reduction of phospholemman expression decreases osmosensitive taurine efflux in astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IMP

regulation of ion transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IEA

regulation of cytosolic calcium ion concentration

1 reference

14 February 2019

Effects of phospholemman downregulation on contractility and [Ca(2+)]i transients in adult rat cardiac myocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IMP

regulation of cardiac muscle cell contraction

1 reference

14 February 2019

Effects of phospholemman downregulation on contractility and [Ca(2+)]i transients in adult rat cardiac myocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IMP

positive regulation of sodium ion export across plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

ISS

positive regulation of inorganic anion transmembrane transport

1 reference

14 February 2019

Reduction of phospholemman expression decreases osmosensitive taurine efflux in astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IMP

regulation of sodium ion transmembrane transporter activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08589

determination method

IBA

Identifiers

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

7 September 2021

1 reference

17 November 2021

1 reference

(Q28562058)

FXYD domain-containing ion transport regulator 1

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