(Q28562487)

http://www.ebi.ac.uk/interpro/protein/O35274

Neurabin-2

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35274

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein kinase activity

1 reference

14 February 2019

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein phosphatase inhibitor activity

1 reference

14 February 2019

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

9 references

14 February 2019

Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Flexibility in the PP1:spinophilin holoenzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein C-terminus binding

1 reference

14 February 2019

Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein phosphatase 1 binding

5 references

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

D2 dopamine receptor binding

1 reference

14 February 2019

Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

transmembrane transporter binding

1 reference

14 February 2019

Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein-containing complex binding

1 reference

14 February 2019

Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

In vivo dynamics of the F-actin-binding protein neurabin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

14 February 2019

Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

3 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cortical actin cytoskeleton

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

2 references

dendritic spine membrane

1 reference

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

In vivo dynamics of the F-actin-binding protein neurabin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cytoplasmic side of dendritic spine plasma membrane

1 reference

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

regulation of protein phosphorylation

biological process

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

A sensitizing D-amphetamine dose regimen induces long-lasting spinophilin and VGLUT1 protein upregulation in the rat diencephalon

response to amphetamine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

developmental process involved in reproduction

1 reference

14 February 2019

Postpubertal decrease in hippocampal dendritic spines of female rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein phosphorylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Dopamine depletion alters phosphorylation of striatal proteins in a model of Parkinsonism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Aging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

response to organonitrogen compound

1 reference

14 February 2019

Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

response to organic cyclic compound

1 reference

14 February 2019

Exploration of prostanoid receptor subtype regulating estradiol and prostaglandin E2 induction of spinophilin in developing preoptic area neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

GnRH receptor gene expression in the developing rat hippocampus: transcriptional regulation and potential roles in neuronal plasticity

ISS

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cerebral cortex development

1 reference

14 February 2019

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

actin filament depolymerization

1 reference

14 February 2019

In vivo dynamics of the F-actin-binding protein neurabin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

neuron projection development

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamus

IBA

response to estradiol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

negative regulation of phosphoprotein phosphatase activity

response to prostaglandin E

IMP

1 reference

14 February 2019

Prostaglandin E2 stimulates estradiol synthesis in the cerebellum postnatally with associated effects on Purkinje neuron dendritic arbor and electrophysiological properties.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Nicotine-induced anxiety-like behavior in a rat model of the novelty-seeking phenotype is associated with long-lasting neuropeptidergic and neuroplastic adaptations in the amygdala: effects of the cannabinoid receptor 1 antagonist AM251

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

response to immobilization stress

1 reference

14 February 2019

Wistar rats subjected to chronic restraint stress display increased hippocampal spine density paralleled by increased expression levels of synaptic scaffolding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamus

response to amino acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

response to steroid hormone

ISS

1 reference

14 February 2019

Methamphetamine enhances paced mating behaviors and neuroplasticity in the medial amygdala of female rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

modulation of chemical synaptic transmission

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

14 February 2019

Identification of prostaglandin E2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

reproductive system development

1 reference

14 February 2019

Postpubertal decrease in hippocampal dendritic spines of female rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cellular response to epidermal growth factor stimulus

1 reference

14 February 2019

In vivo dynamics of the F-actin-binding protein neurabin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cellular response to estradiol stimulus

1 reference

14 February 2019

Estrogenic agonist activity of ICI 182,780 (Faslodex) in hippocampal neurons: implications for basic science understanding of estrogen signaling and development of estrogen modulators with a dual therapeutic profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cellular response to organic cyclic compound

1 reference

14 February 2019

Estrogenic agonist activity of ICI 182,780 (Faslodex) in hippocampal neurons: implications for basic science understanding of estrogen signaling and development of estrogen modulators with a dual therapeutic profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

Clozapine and haloperidol differentially regulate dendritic spine formation and synaptogenesis in rat hippocampal neurons

response to clozapine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

cellular response to peptide

1 reference

14 February 2019

GnRH receptor gene expression in the developing rat hippocampus: transcriptional regulation and potential roles in neuronal plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

positive regulation of protein localization to plasma membrane

1 reference

14 February 2019

Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein localization to actin cytoskeleton

1 reference

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

positive regulation of protein localization

IMP

1 reference

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

positive regulation of protein localization to actin cortical patch

1 reference

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamus

IMP

response to kainic acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

response to L-phenylalanine derivative

1 reference

14 February 2019

Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

protein localization to cell periphery

1 reference

14 February 2019

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35274

1 reference

InterPro Release 71.0