(Q28563210)

Frizzled cysteine-rich domain superfamily

1 reference

stated in

membrane protein

1 reference

inferred from GOA cell component → membrane

Frizzled/Smoothened, transmembrane domain, protein family

1 reference

inferred from protein domain or family

GPCR, family 2-like

1 reference

inferred from protein domain or family

Frizzled domain, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

transmembrane signaling receptor activity

ND

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

G protein-coupled receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Expression of Patched-1 and Smoothened in testicular meiotic and post-meiotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

2 references

integral component of membrane

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron

IDA

dendritic growth cone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

osteoblast differentiation

IDA

biological process

1 reference

14 February 2019

Hedgehog pathway is associated with the proliferation and differentiation of osteoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

determination of left/right asymmetry in lateral mesoderm

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

cell surface receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

smoothened signaling pathway

positive regulation of hh target transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

Expression of Patched-1 and Smoothened in testicular meiotic and post-meiotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

central nervous system development

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

14 February 2019

The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

response to organic substance

1 reference

14 February 2019

Monoaminergic regulation of Sonic hedgehog signaling cascade expression in the adult rat hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

positive regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

negative regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy

facial nerve development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

neuron projection regeneration

1 reference

14 February 2019

The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

Hedgehog pathway is associated with the proliferation and differentiation of osteoblasts

osteoblast proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

negative regulation of DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

negative regulation of neuron apoptotic process

1 reference

14 February 2019

Sonic hedgehog protects cortical neurons against oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

positive regulation of smoothened signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

axon extension involved in axon guidance

IBA

1 reference

14 February 2019

Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

forebrain morphogenesis

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

mesenchymal to epithelial transition involved in metanephric renal vesicle formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

positive regulation of branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

negative regulation of neuron death

1 reference

14 February 2019

Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

positive regulation of vascular associated smooth muscle cell migration

1 reference

14 February 2019

Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

positive regulation of neural precursor cell proliferation

1 reference

14 February 2019

Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97698

1 reference

GPCR, family 2-like

1 reference

stated in

Frizzled/Smoothened, transmembrane domain

1 reference

stated in