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(Q29515892)
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English
Solute carrier family 7 member 11
mammalian protein found in Rattus norvegicus
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Slc7a11
cystine/glutamate transporter
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4ADU2
part of
L-type amino acid transporter
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4ADU2
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4ADU2
encoded by
Slc7a11
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4ADU2
molecular function
molecular function
determination method
ND
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
ND
L-amino acid transmembrane transporter activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IBA
transmembrane transporter activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
cell component
rough endoplasmic reticulum
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IDA
cytoskeleton
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IDA
plasma membrane
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IDA
cell surface
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
membrane
determination method
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4ADU2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
integral component of membrane
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4ADU2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
brush border membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
intracellular membrane-bounded organelle
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IDA
astrocyte projection
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
biological process
glutathione metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
amino acid transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
response to oxidative stress
determination method
IEP
1 reference
retrieved
14 February 2019
stated in
Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEP
brain development
determination method
IEA
IEP
2 references
retrieved
14 February 2019
stated in
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
visual learning
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
response to toxic substance
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
response to organic cyclic compound
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
ventricular system development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
striatum development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
adult behavior
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of neutrophil apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
cellular response to oxidative stress
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
glutathione transmembrane transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
response to nicotine
determination method
IEP
1 reference
retrieved
14 February 2019
stated in
The role of cystine-glutamate exchange in nicotine dependence in rats and humans
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEP
regulation of cell population proliferation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of melanin biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
lung alveolus development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
modulation of chemical synaptic transmission
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of synapse organization
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of protein transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
response to redox state
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
transmembrane transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
limb development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
lens fiber cell differentiation
determination method
IEP
1 reference
retrieved
14 February 2019
stated in
Molecular characterization of the cystine/glutamate exchanger and the excitatory amino acid transporters in the rat lens
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEP
platelet aggregation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
organic substance transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
glutamate homeostasis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
L-glutamate import across plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
dipeptide import across plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of cellular response to oxidative stress
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of cysteine metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
negative regulation of oxidative stress-induced neuron death
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of glutathione biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of AMPA glutamate receptor clustering
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
regulation of glutamate metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4ADU2
determination method
IEA
Identifiers
RefSeq protein ID
NP_001101143
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
310392
XP_038958186
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
310392
XP_038958187
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
310392
XP_038958188
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
310392
UniProt protein ID
D4ADU2
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4ADU2
Ensembl protein ID
ENSRNOP00000014317
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000014317
ENSRNOP00000091221
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000091221
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Multilingual sites
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