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English
Endoplasmic reticulum to nucleus signaling 2
mammalian protein found in Rattus norvegicus
Ern2
endoplasmic reticulum (ER) to nucleus signalling 2
serine/threonine-protein kinase/endoribonuclease IRE2
In more languages
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No label defined
No description defined
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZTI7
part of
Quinoprotein alcohol dehydrogenase-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
Serine/threonine-protein kinase/endoribonuclease IRE2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
KEN domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
WD40/YVTN repeat-like-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
KEN domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
PUB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Pyrrolo-quinoline quinone beta-propeller repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZTI7
encoded by
Ern2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZTI7
molecular function
magnesium ion binding
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
endonuclease activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
ribonuclease activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
protein kinase activity
determination method or standard
IEA
1 reference
retrieved
11 October 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZTI7&geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
protein serine/threonine kinase activity
determination method or standard
IEA
1 reference
retrieved
11 October 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZTI7&geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
ATP binding
determination method or standard
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
endoribonuclease activity
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
protein kinase activity
determination method or standard
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
protein serine/threonine kinase activity
determination method or standard
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
unfolded protein binding
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
cell component
IRE1-TRAF2-ASK1 complex
determination method or standard
IEA
1 reference
retrieved
11 October 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZTI7&geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
endoplasmic reticulum membrane
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
IRE1-TRAF2-ASK1 complex
determination method or standard
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
biological process
regulation of transcription, DNA-templated
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
mRNA processing
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
protein phosphorylation
determination method or standard
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
rRNA catabolic process
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
apoptotic chromosome condensation
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
response to endoplasmic reticulum stress
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
negative regulation of transcription, DNA-templated
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
determination method or standard
IEA
1 reference
retrieved
11 October 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZTI7&geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
nucleic acid phosphodiester bond hydrolysis
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
RNA phosphodiester bond hydrolysis
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
endoplasmic reticulum unfolded protein response
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
IRE1-mediated unfolded protein response
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
determination method or standard
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IBA
RNA phosphodiester bond hydrolysis, endonucleolytic
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZTI7
determination method or standard
IEA
has part(s)
Pyrrolo-quinoline quinone beta-propeller repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
PUB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
KEN domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZTI7
Identifiers
RefSeq protein ID
NP_001102389
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
365363
XP_038941189
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
365363
UniProt protein ID
D3ZTI7
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZTI7
Ensembl protein ID
ENSRNOP00000025699
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000025699
Sitelinks
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Multilingual sites
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