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English
Serine/threonine kinase 4
mammalian protein found in Rattus norvegicus
Stk4
serine/threonine-protein kinase 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4A648
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A648
Mst1 SARAH domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
SARAH domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4A648
encoded by
Stk4
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4A648
molecular function
magnesium ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein kinase activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
ATP binding
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
transcription factor binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
identical protein binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein homodimerization activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein dimerization activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein serine/threonine kinase activity
determination method
IBA
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
cell component
nucleus
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
nucleoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
cytoplasm
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
cytosol
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
nuclear body
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein-containing complex
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
biological process
cell morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
branching involved in blood vessel morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
neural tube formation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of protein phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
endocardium development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein phosphorylation
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
central nervous system development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
negative regulation of cell population proliferation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
peptidyl-serine phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
keratinocyte differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of protein binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of peptidyl-serine phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
hippo signaling
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
intracellular signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of fat cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
negative regulation of organ growth
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein autophosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
protein stabilization
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
primitive hemopoiesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
cell differentiation involved in embryonic placenta development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
regulation of cell differentiation involved in embryonic placenta development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
hepatocyte apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
regulation of mitotic cell cycle
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D4A648&geneProductId=UniProtKB:D4A648
determination method
IBA
signal transduction
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
stress-activated protein kinase signaling cascade
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
activation of protein kinase activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IBA
regulation of apoptotic process
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D4A648&geneProductId=UniProtKB:D4A648
determination method
IBA
negative regulation of canonical Wnt signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IEA
positive regulation of vascular associated smooth muscle cell apoptotic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
MicroRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1.
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A648
determination method
IMP
has part(s)
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A648
SARAH domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A648
Mst1 SARAH domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A648
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A648
Identifiers
RefSeq protein ID
NP_001101270
1 reference
stated in
NCBI Gene
retrieved
7 September 2021
Entrez Gene ID
311622
XP_038961057
1 reference
stated in
NCBI Gene
retrieved
7 September 2021
Entrez Gene ID
311622
XP_038961058
1 reference
stated in
NCBI Gene
retrieved
7 September 2021
Entrez Gene ID
311622
UniProt protein ID
D4A648
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D4A648
Sitelinks
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Wikiquote
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Wikisource
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Multilingual sites
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