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Left right determination factor 1
mammalian protein found in Rattus norvegicus
left-right determination factor 1
Lefty1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D4A670
part of
Left- Right determination factor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A670
Cystine-knot cytokine
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A670
Transforming growth factor-beta, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
TGF-beta, propeptide family
1 reference
based on heuristic
inferred from protein domain or family
Transforming growth factor beta, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D4A670
encoded by
Lefty1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D4A670
molecular function
cytokine activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D4A670&geneProductId=UniProtKB:D4A670
determination method
IBA
transforming growth factor beta receptor binding
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
growth factor activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A670
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
nodal binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
cytokine activity
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A670
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
cell component
extracellular region
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A670
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D4A670&geneProductId=UniProtKB:D4A670
determination method
IBA
extracellular space
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A670
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
biological process
negative regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
heart morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
determination of left/right symmetry
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
negative regulation of cell population proliferation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
anterior/posterior axis specification
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
positive regulation of pathway-restricted SMAD protein phosphorylation
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
BMP signaling pathway
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D4A670&geneProductId=UniProtKB:D4A670
determination method
IBA
response to retinoic acid
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
cell migration involved in gastrulation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
regulation of apoptotic process
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
regulation of MAPK cascade
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
cell development
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
SMAD protein signal transduction
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IBA
negative regulation of nodal signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
negative regulation of nodal receptor complex assembly
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D4A670
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D4A670
determination method
IEA
has part(s)
TGF-beta, propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A670
Transforming growth factor beta, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A670
Transforming growth factor-beta, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D4A670
Identifiers
RefSeq protein ID
NP_001102550
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
498299
XP_038946918
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
498299
UniProt protein ID
D4A670
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D4A670
Ensembl protein ID
ENSRNOP00000004354
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000004354
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