(Q29526036)

von Willebrand factor A-like domain superfamily

1 reference

Integrin domain superfamily

1 reference

Integrin beta tail domain superfamily

1 reference

Integrin beta subunit, cytoplasmic domain, protein family

1 reference

Integrin beta subunit, tail, protein family

1 reference

Integrin beta subunit, VWA domain, protein family

1 reference

Integrin beta N-terminal domain, protein family

1 reference

EGF-like domain, extracellular domain, protein family

1 reference

PSI domain, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

IEA

fibrinogen binding

1 reference

9 May 2019

RGD-containing peptides inhibit fibrinogen binding to platelet alpha(IIb)beta3 by inducing an allosteric change in the amino-terminal portion of alpha(IIb)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

cell component

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

TAS

focal adhesion

1 reference

9 May 2019

β(1) and β(3) integrins disassemble from basal focal adhesions and β(3) integrin is later localised to the apical plasma membrane of rat uterine luminal epithelial cells at the time of implantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

cell surface

1 reference

9 May 2019

RGD-containing peptides inhibit fibrinogen binding to platelet alpha(IIb)beta3 by inducing an allosteric change in the amino-terminal portion of alpha(IIb)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

IEA

apical plasma membrane

1 reference

9 May 2019

β(1) and β(3) integrins disassemble from basal focal adhesions and β(3) integrin is later localised to the apical plasma membrane of rat uterine luminal epithelial cells at the time of implantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

positive regulation of leukocyte migration

ISS

biological process

1 reference

9 May 2019

Platelets modulate ischemia/reperfusion-induced leukocyte recruitment in the mesenteric circulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

cell adhesion

Temporal response and localization of integrins beta1 and beta3 in the heart after myocardial infarction: regulation by cytokines

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

9 May 2019

IEA

embryo implantation

1 reference

9 May 2019

Demonstration of uterine receptivity in vitro by co-culture of rat epithelial cells and blastocyst

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

regulation of G protein-coupled receptor signaling pathway

1 reference

9 May 2019

Integrins regulate opioid receptor signaling in trigeminal ganglion neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

response to radiation

1 reference

9 May 2019

Low-energy laser irradiation facilitates the velocity of tooth movement and the expressions of matrix metalloproteinase-9, cathepsin K, and alpha(v) beta(3) integrin in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of fibroblast migration

1 reference

9 May 2019

Estrogen attenuates integrin-beta(3)-dependent adventitial fibroblast migration after inhibition of osteopontin production in vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

response to activity

1 reference

9 May 2019

Prolonged exercise induces angiogenesis and increases cerebral blood volume in primary motor cortex of the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of smooth muscle cell migration

2 references

9 May 2019

Increased static pressure promotes migration of vascular smooth muscle cells: involvement of the Rho-kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

9 May 2019

Latent transforming growth factor-beta binding protein-1, a component of latent transforming growth factor-beta complex, accelerates the migration of aortic smooth muscle cells in diabetic rats through integrin-beta3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of cell adhesion mediated by integrin

1 reference

9 May 2019

Blockade of integrin beta3-FAK signaling pathway activated by osteopontin inhibits neointimal formation after balloon injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

response to platelet-derived growth factor

1 reference

9 May 2019

Combined effects of platelet-derived growth factor-BB and insulin-like growth factor-I on the expression of integrin (beta 3 protein in periodontal ligament cells of rats during orthodontic tooth movement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of angiogenesis

1 reference

9 May 2019

Inhibition of in vivo tumour growth by the blocking of host alpha(v)beta3 and alphaII(b)beta3 integrins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of bone resorption

1 reference

9 May 2019

Antibody to beta3 integrin inhibits osteoclast-mediated bone resorption in the thyroparathyroidectomized rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of smooth muscle cell proliferation

1 reference

9 May 2019

Intermittent high glucose enhances proliferation of vascular smooth muscle cells by upregulating osteopontin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

regulation of release of sequestered calcium ion into cytosol

1 reference

9 May 2019

Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

negative regulation of cell death

1 reference

9 May 2019

NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of ERK1 and ERK2 cascade

1 reference

9 May 2019

P2Y nucleotide receptor signaling through MAPK/ERK is regulated by extracellular matrix: involvement of beta3 integrins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

cellular response to mechanical stimulus

1 reference

9 May 2019

The effect of mechanical stimulation on the expression of alpha 2, beta 1, beta 3 integrins and the proliferation, synthetic function in rat osteoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of glomerular mesangial cell proliferation

1 reference

9 May 2019

Involvement of osteopontin upregulation on mesangial cells growth and collagen synthesis induced by intermittent high glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

1 reference

9 May 2019

Integrins regulate opioid receptor signaling in trigeminal ganglion neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

cellular response to insulin-like growth factor stimulus

1 reference

9 May 2019

Combined effects of platelet-derived growth factor-BB and insulin-like growth factor-I on the expression of integrin (beta 3 protein in periodontal ligament cells of rats during orthodontic tooth movement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

regulation of protein localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

regulation of serotonin uptake

ISS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R2H2

1 reference

9 May 2019

1 reference

Integrin beta N-terminal

1 reference

Integrin beta subunit, VWA domain

1 reference

Integrin beta subunit, cytoplasmic domain

1 reference

EGF-like domain, extracellular

1 reference

Integrin beta subunit, tail

1 reference