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SIX homeobox 4
mammalian protein found in Rattus norvegicus
sine oculis-related homeobox 4 homolog
Six4
homeobox protein SIX4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZAJ7
part of
Homeobox-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZAJ7
Homeobox domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox protein SIX1, N-terminal SD domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZAJ7
encoded by
Six4
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZAJ7
molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IEA
2 references
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
DNA binding
determination method
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D3ZAJ7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
DNA-binding transcription factor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
sequence-specific DNA binding
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
transcription cis-regulatory region binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
cell component
nucleus
determination method
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
D3ZAJ7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
nucleus
determination method
IBA
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D3ZAJ7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
transcription regulator complex
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
biological process
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
skeletal muscle tissue development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
regulation of synaptic assembly at neuromuscular junction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
male gonad development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
regulation of gene expression
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
male sex determination
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
olfactory placode formation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
regulation of protein localization
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
protein localization to nucleus
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
inner ear morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
negative regulation of apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
negative regulation of neuron apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
tongue development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
sarcomere organization
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
negative regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
positive regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
male sex differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
thymus development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
generation of neurons
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
embryonic cranial skeleton morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
embryonic skeletal system morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
anatomical structure development
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZAJ7&geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
regulation of epithelial cell proliferation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
myoblast migration
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
pharyngeal system development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
myotome development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
fungiform papilla morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
trigeminal ganglion development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
metanephric mesenchyme development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
regulation of branch elongation involved in ureteric bud branching
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
positive regulation of ureteric bud formation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
positive regulation of branching involved in ureteric bud morphogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
skeletal muscle fiber differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
negative regulation of satellite cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
negative regulation of transcription, DNA-templated
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
anatomical structure development
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZAJ7
determination method
IBA
has part(s)
Homeobox domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZAJ7
Homeobox, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZAJ7
Homeobox protein SIX1, N-terminal SD domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZAJ7
Identifiers
RefSeq protein ID
NP_001100209
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
299138
XP_006240269
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
299138
XP_006240270
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
299138
XP_038967927
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
299138
XP_038967928
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
299138
UniProt protein ID
D3ZAJ7
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZAJ7
Ensembl protein ID
ENSRNOP00000050667
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000050667
ENSRNOP00000089936
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000089936
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