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English
Suppressor of cytokine signaling 5
mammalian protein found in Rattus norvegicus
suppressor of cytokine signaling 5
Socs5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZUE4
part of
SOCS box-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
Suppressor of cytokine signalling 5
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
SH2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
SOCS5, SOCS box domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SOCS4/SOCS5 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SOCS box domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZUE4
encoded by
Socs5
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZUE4
molecular function
protein kinase inhibitor activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
epidermal growth factor receptor binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
receptor tyrosine kinase binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
1-phosphatidylinositol-3-kinase regulator activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IBA
cell component
cytoplasm
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IEA
phosphatidylinositol 3-kinase complex
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IBA
biological process
negative regulation of protein kinase activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
epidermal growth factor receptor signaling pathway
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of epidermal growth factor-activated receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
receptor signaling pathway via JAK-STAT
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
cytokine-mediated signaling pathway
determination method
IBA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of interleukin-6 production
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
intracellular signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of epidermal growth factor receptor signaling pathway
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
positive regulation of T-helper 1 cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of T-helper 2 cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of receptor signaling pathway via JAK-STAT
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=D3ZUE4&geneProductId=UniProtKB:D3ZUE4
determination method
IBA
negative regulation of inflammatory response
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
cellular response to low-density lipoprotein particle stimulus
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
negative regulation of monocyte chemotactic protein-1 production
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
vascular endothelial cell response to fluid shear stress
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
protein ubiquitination
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
D3ZUE4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
cytokine-mediated signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
regulation of phosphatidylinositol 3-kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IEA
phosphatidylinositol phosphate biosynthetic process
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZUE4
determination method
IBA
has part(s)
SOCS box domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
SOCS4/SOCS5 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
SOCS5, SOCS box domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZUE4
Identifiers
RefSeq protein ID
NP_001102744
1 reference
stated in
NCBI Gene
retrieved
7 September 2021
Entrez Gene ID
500616
XP_006239780
1 reference
stated in
NCBI Gene
retrieved
7 September 2021
Entrez Gene ID
500616
UniProt protein ID
D3ZUE4
1 reference
stated in
UniProt
retrieved
17 November 2021
UniProt protein ID
D3ZUE4
Ensembl protein ID
ENSRNOP00000020346
1 reference
stated in
ensembl Release 104
Ensembl protein ID
ENSRNOP00000020346
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