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(Q29529106)
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TRAF3 interacting protein 2
mammalian protein found in Mus musculus
adapter protein CIKS
connection to IKK and SAPK/JNK
Traf3ip2
nuclear factor NF-kappa-B activator 1
E3 ubiquitin-protein ligase CIKS
E3 ubiquitin ligase TRAF3IP2
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8N7N6
part of
SEFIR domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8N7N6
encoded by
Traf3ip2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8N7N6
molecular function
signaling receptor binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail
GOA
curator
UniProt
UniProt protein ID
Q8N7N6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IPI
protein binding
determination method
IPI
3 references
retrieved
14 February 2019
stated in
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IPI
retrieved
14 February 2019
stated in
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IPI
retrieved
14 February 2019
stated in
Bioinformatics and cellular signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IPI
biological process
B cell apoptotic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IMP
positive regulation of defense response to virus by host
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IEA
humoral immune response
determination method
IMP
1 reference
retrieved
24 April 2018
stated in
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N7N6&geneProductId=UniProtKB:Q8N7N6
determination method
IMP
positive regulation of I-kappaB kinase/NF-kappaB signaling
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N7N6&geneProductId=UniProtKB:Q8N7N6
determination method
IEA
humoral immune response
determination method
IBA
IMP
2 references
retrieved
14 February 2019
stated in
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IMP
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IBA
positive regulation of I-kappaB kinase/NF-kappaB signaling
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N7N6
determination method
IBA
has part(s)
SEFIR domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N7N6
Identifiers
RefSeq protein ID
NP_598761
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
103213
XP_011241407
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
103213
UniProt protein ID
Q8N7N6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8N7N6
Ensembl protein ID
ENSMUSP00000019987
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000019987
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