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(Q29791898)
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Endoplasmic reticulum chaperone BiP homolog;Heat shock 70 kDa protein D CELE_F43E2.8
Protein found in Caenorhabditis elegans
hsp-4
Heat shock 70 kDa protein D
Heat Shock Protein;Heat shock 70 kDa protein D
Endoplasmic reticulum chaperone BiP homolog;Heat shock 70 kDa protein D
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P20163
part of
Heat shock protein 70kD, peptide-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20163
Heat shock protein 70kD, C-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20163
Heat shock protein 70 family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20163
Heat shock protein 70, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P20163
encoded by
hsp-4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P20163
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P20163
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEA
ATP binding
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P20163
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
hydrolase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P20163
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEA
ATPase activity
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
heat shock protein binding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
protein folding chaperone activity
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
unfolded protein binding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
misfolded protein binding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
cell component
nucleus
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
cytoplasm
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
endoplasmic reticulum
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P20163
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEA
endoplasmic reticulum lumen
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P20163
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
rough endoplasmic reticulum
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The unfolded protein response is required for dendrite morphogenesis
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IDA
membrane
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
endoplasmic reticulum chaperone complex
determination method
IBA
ISS
2 references
retrieved
1 January 2018
stated in
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
ISS
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
biological process
response to unfolded protein
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
ubiquitin-dependent ERAD pathway
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
endoplasmic reticulum unfolded protein response
determination method
HEP
IBA
IEP
6 references
retrieved
1 January 2018
stated in
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEP
retrieved
1 January 2018
stated in
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEP
retrieved
1 January 2018
stated in
APY-1, a novel Caenorhabditis elegans apyrase involved in unfolded protein response signalling and stress responses.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEP
retrieved
1 January 2018
stated in
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IEP
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
retrieved
1 January 2018
stated in
A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
HEP
cellular response to heat
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
Unfolded Protein Response
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
protein refolding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
chaperone cofactor-dependent protein refolding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20163
determination method
IBA
has part(s)
Heat shock protein 70, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20163
Identifiers
RefSeq protein ID
NP_001293470
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
174203
NP_001370395
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
174203
UniProt protein ID
P20163
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P20163
Ensembl protein ID
F43E2.8a.1
1 reference
stated in
ensembl Release 106
Ensembl protein ID
F43E2.8a.1
F43E2.8a.2
1 reference
stated in
ensembl Release 106
Ensembl protein ID
F43E2.8a.2
F43E2.8b.1
1 reference
stated in
ensembl Release 106
Ensembl protein ID
F43E2.8b.1
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