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(Q29793675)
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English
Probable glutathione reductase 2 CELE_ZK637.10
protein found in Caenorhabditis elegans
trxr-2
Probable glutathione reductase 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P30635
part of
FAD/NAD-linked reductase, dimerisation domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
Thioredoxin/glutathione reductase selenoprotein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
FAD/NAD(P)-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
FAD/NAD(P)-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Pyridine nucleotide-disulphide oxidoreductase, class I, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P30635
encoded by
trxr-2
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P30635
molecular function
glutathione-disulfide reductase (NADPH) activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P30635
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
thioredoxin-disulfide reductase activity
determination method
IDA
IEA
2 references
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P30635&geneProductId=UniProtKB:P30635
determination method
IEA
retrieved
16 July 2018
stated in
Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P30635&geneProductId=UniProtKB:P30635
determination method
IDA
electron transfer activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
oxidoreductase activity
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P30635
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
flavin adenine dinucleotide binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
thioredoxin-disulfide reductase activity
determination method
IBA
IDA
IEA
3 references
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
retrieved
1 January 2018
stated in
Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P30635
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P30635&geneProductId=UniProtKB:P30635
determination method
IEA
mitochondrion
determination method
IBA
IDA
2 references
retrieved
1 January 2018
stated in
The characterization of the Caenorhabditis elegans mitochondrial thioredoxin system uncovers an unexpected protective role of thioredoxin reductase 2 in β-amyloid peptide toxicity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IBA
cytoplasm
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P30635
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IBA
biological process
response to oxygen radical
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P30635&geneProductId=UniProtKB:P30635
determination method
IBA
electron transport chain
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
cell redox homeostasis
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IBA
cellular oxidant detoxification
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30635
determination method
IEA
has part(s)
FAD/NAD(P)-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
Pyridine nucleotide-disulphide oxidoreductase, class I, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P30635
Identifiers
RefSeq protein ID
NP_498971
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
176259
UniProt protein ID
P30635
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P30635
Ensembl protein ID
ZK637.10
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ZK637.10
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