(Q29795065)

Prolyl 4-hydroxylase alpha-subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Prolyl 4-hydroxylase, alpha subunit, protein family

1 reference

based on heuristic

inferred from protein domain or family

Oxoglutarate/iron-dependent dioxygenase family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

procollagen-proline 4-dioxygenase activity

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

16 July 2018

Three binding sites in protein-disulfide isomerase cooperate in collagen prolyl 4-hydroxylase tetramer assembly.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

oxidoreductase activity

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

2 references

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

L-ascorbic acid binding

peptidyl-proline 4-dioxygenase activity

2 references

1 reference

1 January 2018

A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

procollagen-proline 4-dioxygenase activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 January 2018

Three binding sites in protein-disulfide isomerase cooperate in collagen prolyl 4-hydroxylase tetramer assembly.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

IBA

cell component

endoplasmic reticulum

3 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

16 July 2018

The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10576&geneProductId=UniProtKB:Q10576

endoplasmic reticulum lumen

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

endoplasmic reticulum

4 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 January 2018

The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

embryo development ending in birth or egg hatching

IBA

biological process

1 reference

1 January 2018

Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

embryonic body morphogenesis

IMP

1 reference

1 January 2018

Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

peptidyl-proline hydroxylation

IGI

1 reference

1 January 2018

Three binding sites in protein-disulfide isomerase cooperate in collagen prolyl 4-hydroxylase tetramer assembly.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

collagen and cuticulin-based cuticle development

IDA

1 reference

1 January 2018

Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

positive regulation of multicellular organism growth

IMP

1 reference

1 January 2018

Regulation of Caenorhabditis elegans body size and male tail development by the novel gene lon-8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

cuticle development involved in collagen and cuticulin-based cuticle molting cycle

IGI

1 reference

1 January 2018

Caenorhabditis elegans exoskeleton collagen COL-19: an adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

macromolecule modification

IMP

1 reference

1 January 2018

A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

peptidyl-proline hydroxylation to 4-hydroxy-L-proline

IDA

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q10576

Oxoglutarate/iron-dependent dioxygenase

IBA

has part(s)

1 reference

Prolyl 4-hydroxylase, alpha subunit

1 reference

Prolyl 4-hydroxylase alpha-subunit, N-terminal

1 reference