(Q29801490)

Cystine-knot cytokine

1 reference

Transforming growth factor-beta, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TGF-beta, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Transforming growth factor beta, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

transforming growth factor beta receptor binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans.

growth factor activity

2 references

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

nematode larval development

IEA

biological process

1 reference

1 January 2018

The expression of TGFbeta signal transducers in the hypodermis regulates body size in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

transforming growth factor beta receptor signaling pathway

regulation of gene expression

1 reference

1 January 2018

Specificity and complexity of the Caenorhabditis elegans innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

regulation of signaling receptor activity

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of pathway-restricted SMAD protein phosphorylation

IEA

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

regulation of cell morphogenesis

1 reference

1 January 2018

CEH-28 activates dbl-1 expression and TGF-β signaling in the C. elegans M4 neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of transforming growth factor beta receptor signaling pathway

1 reference

1 January 2018

Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of DNA endoreduplication

IGI

1 reference

1 January 2018

Increased or decreased levels of Caenorhabditis elegans lon-3, a gene encoding a collagen, cause reciprocal changes in body length.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of multicellular organism growth

7 references

1 January 2018

Hypodermal expression of Caenorhabditis elegans TGF-beta type I receptor SMA-6 is essential for the growth and maintenance of body length.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

The expression of TGFbeta signal transducers in the hypodermis regulates body size in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

Genetic screen for small body size mutants in C. elegans reveals many TGFbeta pathway components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

Cyclic GMP-dependent protein kinase EGL-4 controls body size and lifespan in C elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

lon-1 regulates Caenorhabditis elegans body size downstream of the dbl-1 TGF beta signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

Glypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

C. elegans serine-threonine kinase KIN-29 modulates TGFbeta signaling and regulates body size formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

regulation of mesodermal cell fate specification

IGI

1 reference

1 January 2018

Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

regulation of apoptotic process

IGI

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

regulation of MAPK cascade

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-beta signaling pathway in Caenorhabditis elegans epidermis

innate immune response

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

nematode male tail tip morphogenesis

1 reference

1 January 2018

Genetic screen for small body size mutants in C. elegans reveals many TGFbeta pathway components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of cell size

1 reference

1 January 2018

The expression of TGFbeta signal transducers in the hypodermis regulates body size in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of transcription by RNA polymerase II

1 reference

1 January 2018

Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-beta signaling pathway in Caenorhabditis elegans epidermis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

positive regulation of organ growth

1 reference

1 January 2018

The expression of TGFbeta signal transducers in the hypodermis regulates body size in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

SMAD protein signal transduction

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth

3 references

1 January 2018

Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 January 2018

Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEL5

1 reference

Transforming growth factor beta, conserved site

1 reference

Transforming growth factor-beta, C-terminal

1 reference