(Q29801654)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q03614

Transporter Classification Database ID

2.A.22.1.4

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Sodium:neurotransmitter symporter superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q03614

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

chloride channel activity

1 reference

1 January 2018

Dopamine transporters depolarize neurons by a channel mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

amine transmembrane transporter activity

1 reference

1 January 2018

Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

neurotransmitter:sodium symporter activity

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

dopamine:sodium symporter activity

3 references

16 July 2018

The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

16 July 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

16 July 2018

Dopamine transporters depolarize neurons by a channel mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

dopamine:sodium symporter activity

4 references

1 January 2018

The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

Dopamine transporters depolarize neurons by a channel mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

integral component of plasma membrane

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

neuronal cell body membrane

1 reference

16 July 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

1 reference

16 July 2018

Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03614&geneProductId=UniProtKB:Q03614

neuronal cell body membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

Dopamine transporters depolarize neurons by a channel mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

neurotransmitter transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

IMP

transmembrane transport

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 reference

1 January 2018

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

positive regulation of neuron death

2 references

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

chloride transmembrane transport

IGI

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

negative regulation of cellular response to manganese ion

1 reference

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

negative regulation of cellular response to oxidopamine

IGI

1 reference

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IMP

norepinephrine transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

dopamine uptake involved in synaptic transmission

IBA

3 references

1 January 2018

The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

Dopamine transporters depolarize neurons by a channel mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03614

Transporter Classification Database ID

IBA

Identifiers

1 reference

14 December 2018

1 reference

5 December 2018

1 reference

2.A.22.1.4

2 references

Transporter Classification database

retrieved

13 March 2020