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(Q29804151)
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1;Phosphoinositide phospholipase C CELE_F31B12.1
protein found in Caenorhabditis elegans
plc-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1;Phosphoinositide phospholipase C
Phosphoinositide phospholipase C
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
G5EFI8
part of
Ubiquitin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Ras guanine-nucleotide exchange factor catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
C2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Ras guanine nucleotide exchange factor domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
EF-hand domain pair
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Ras-associating (RA) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ras guanine-nucleotide exchange factors catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
C2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Phosphatidylinositol-specific phospholipase C, X domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Phospholipase C, phosphatidylinositol-specific, Y domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Phosphoinositide-specific phospholipase C, EF-hand-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
G5EFI8
encoded by
plc-1
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
G5EFI8
molecular function
phosphatidylinositol phospholipase C activity
determination method
IDA
IEA
3 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
5 June 2018
stated in
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IDA
signal transducer activity
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IEA
guanyl-nucleotide exchange factor activity
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
phosphoric diester hydrolase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
GTPase inhibitor activity
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IDA
phosphatidylinositol phospholipase C activity
determination method
IBA
IDA
IEA
4 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
1 January 2018
stated in
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
protein binding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
cell component
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IEA
biological process
activation of immune response
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IMP
lipid metabolism
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
signal transduction
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
negative regulation of adenylate cyclase activity
determination method
IDA
1 reference
retrieved
24 April 2018
stated in
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EFI8&geneProductId=UniProtKB:G5EFI8
determination method
IDA
small GTPase mediated signal transduction
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
determination of adult lifespan
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IMP
lipid catabolic process
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
intracellular signal transduction
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
defense response to Gram-positive bacterium
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IMP
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IDA
positive regulation of protein import into nucleus
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense
GOA
curator
UniProt
UniProt protein ID
G5EFI8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IMP
negative regulation of GTPase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IEA
Ras protein signal transduction
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
inositol trisphosphate biosynthetic process
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
phosphatidylinositol-mediated signaling
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
release of sequestered calcium ion into cytosol
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFI8
determination method
IBA
has part(s)
Phosphoinositide-specific phospholipase C, EF-hand-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Phospholipase C, phosphatidylinositol-specific, Y domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Phosphatidylinositol-specific phospholipase C, X domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Ras guanine-nucleotide exchange factors catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
C2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Ras-associating (RA) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFI8
Identifiers
RefSeq protein ID
NP_001024617
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
NP_001024619
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
NP_001123141
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
NP_001129926
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
NP_001129927
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
NP_509805
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
181274
UniProt protein ID
G5EFI8
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
G5EFI8
Ensembl protein ID
F31B12.1b
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1b
F31B12.1e
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1e
F31B12.1d
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1d
F31B12.1f
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1f
F31B12.1a
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1a
F31B12.1c
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F31B12.1c
Sitelinks
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Wikiquote
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Wikisource
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Multilingual sites
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