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Mitogen-activated protein kinase kinase kinase dlk-1 CELE_F33E2.2
protein found in Caenorhabditis elegans
Mitogen-activated protein kinase kinase kinase dlk-1
dlk-1
Dual-Leucine zipper Kinase;Mitogen-activated protein kinase kinase kinase dlk-1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
O01700
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O01700
mitogen-activated protein kinase kinase kinase 12/13
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O01700
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
O01700
encoded by
dlk-1
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
O01700
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
protein kinase activity
determination method
IBA
IEA
2 references
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O01700&geneProductId=UniProtKB:O01700
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O01700&geneProductId=UniProtKB:O01700
determination method
IBA
protein serine/threonine kinase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
MAP kinase kinase kinase activity
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
signal transducer activity
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O01700&geneProductId=UniProtKB:O01700
determination method
IBA
ATP binding
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
ubiquitin protein ligase binding
determination method
IPI
1 reference
retrieved
1 January 2018
stated in
Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IPI
metal ion binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
protein kinase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
cell component
intracellular anatomical structure
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O01700&geneProductId=UniProtKB:O01700
determination method
IBA
cytoplasm
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
cilium
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
cell junction
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
axon
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
dendrite
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
cell projection
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
neuronal cell body
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The ubiquitin ligase RPM-1 and the p38 MAPK PMK-3 regulate AMPA receptor trafficking
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IDA
synapse
determination method
IDA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
retrieved
1 January 2018
stated in
Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IDA
biological process
protein phosphorylation
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
phosphorylation
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
axon regeneration
determination method
IGI
2 references
retrieved
1 January 2018
stated in
Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
retrieved
1 January 2018
stated in
The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
positive regulation of axon extension
determination method
IGI
1 reference
retrieved
1 January 2018
stated in
RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
protein autophosphorylation
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IEA
axon extension involved in regeneration
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Axon regeneration requires a conserved MAP kinase pathway.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IMP
formation of growth cone in injured axon
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Axon regeneration requires a conserved MAP kinase pathway.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IMP
positive regulation of axon extension involved in regeneration
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IMP
regulation of axon extension involved in axon guidance
determination method
IGI
1 reference
retrieved
1 January 2018
stated in
The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
regulation of synapse organization
determination method
IGI
1 reference
retrieved
1 January 2018
stated in
Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
regulation of 3'-UTR-mediated mRNA stabilization
determination method
IGI
1 reference
retrieved
1 January 2018
stated in
The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration
GOA
curator
UniProt
UniProt protein ID
O01700
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IGI
p38MAPK cascade
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Axon regeneration requires a conserved MAP kinase pathway.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O01700
determination method
IMP
has part(s)
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O01700
serine-threonine/tyrosine-protein kinase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O01700
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O01700
Identifiers
RefSeq protein ID
NP_001021443
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
173128
NP_001021444
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
173128
NP_001021445
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
173128
NP_001129769
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
173128
NP_001251937
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
173128
UniProt protein ID
O01700
1 reference
stated in
UniProt
retrieved
10 April 2019
UniProt protein ID
O01700
Ensembl protein ID
F33E2.2e.2
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2e.2
F33E2.2d
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2d
F33E2.2c
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2c
F33E2.2b
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2b
F33E2.2a
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2a
F33E2.2e.1
1 reference
stated in
ensembl Release 96
Ensembl protein ID
F33E2.2e.1
Sitelinks
Wikipedia
(0 entries)
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
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Wikivoyage
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Multilingual sites
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