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RAB family CELE_D1037.4
Protein found in Caenorhabditis elegans
RAB family
rab-8
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
G5EFC1
part of
small GTPase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFC1
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFC1
Small GTP-binding protein domain family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
G5EFC1
encoded by
rab-8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
G5EFC1
molecular function
GTPase activity
determination method
IBA
IEA
ISS
3 references
retrieved
1 January 2018
stated in
Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
ISS
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
protein binding
determination method
IPI
2 references
retrieved
1 January 2018
stated in
EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IPI
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IPI
GTP binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IEA
GTPase activating protein binding
determination method
IPI
1 reference
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IPI
ankyrin repeat binding
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
cell component
endosome
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
plasma membrane
determination method
HDA
IBA
2 references
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
retrieved
1 January 2018
stated in
Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
HDA
synaptic vesicle
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
endosome membrane
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IDA
apical plasma membrane
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The Rab8 GTPase regulates apical protein localization in intestinal cells
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IDA
transport vesicle
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IDA
trans-Golgi network transport vesicle
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
apical cortex
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The Rab8 GTPase regulates apical protein localization in intestinal cells
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IDA
recycling endosome membrane
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IDA
biological process
reproduction
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
intracellular protein transport
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
vesicle docking involved in exocytosis
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
protein secretion
determination method
IBA
IMP
2 references
retrieved
1 January 2018
stated in
Clathrin interaction and subcellular localization of Ce-DAB-1, an adaptor for protein secretion in Caenorhabditis elegans
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
regulation of exocytosis
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
embryonic genitalia morphogenesis
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
Rab protein signal transduction
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
cellular response to insulin stimulus
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
Golgi vesicle fusion to target membrane
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
protein localization to plasma membrane
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IBA
negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
positive regulation of establishment of protein localization
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
GOA
curator
UniProt
UniProt protein ID
G5EFC1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EFC1
determination method
IMP
has part(s)
small GTP-binding protein domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/G5EFC1
Identifiers
RefSeq protein ID
NP_491199
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
171935
UniProt protein ID
G5EFC1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
G5EFC1
Ensembl protein ID
D1037.4.1
1 reference
stated in
ensembl Release 106
Ensembl protein ID
D1037.4.1
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