(Q29808679)

http://www.ebi.ac.uk/interpro/protein/Q9U1S7

InterPro Release 71.0

reference URL

polycystin cation channel

1 reference

Transporter Classification Database ID

1.A.5.2.4

hierarchical database ID heuristic

2 October 2019

based on heuristic

Polycystin cation channel, PKD1/PKD2, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

calcium channel activity

1 reference

24 April 2018

Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9U1S7&geneProductId=UniProtKB:Q9U1S7

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

endoplasmic reticulum membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

3 references

1 January 2018

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

cilium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

4 references

1 January 2018

1 January 2018

General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9U1S7&geneProductId=UniProtKB:Q9U1S7

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9U1S7&geneProductId=UniProtKB:Q9U1S7

24 April 2018

24 April 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9U1S7&geneProductId=UniProtKB:Q9U1S7

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

axon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

3 references

1 January 2018

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

dendrite

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

5 references

1 January 2018

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

STAM and Hrs down-regulate ciliary TRP receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

organelle membrane

1 reference

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

soma

8 references

1 January 2018

Casein kinase II and calcineurin modulate TRPP function and ciliary localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

STAM and Hrs down-regulate ciliary TRP receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Towards understanding the polycystins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

perikaryon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

perinuclear region of cytoplasm

1 reference

1 January 2018

Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

sensory dendrite

1 reference

1 January 2018

Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

non-motile cilium

6 references

1 January 2018

Casein kinase II and calcineurin modulate TRPP function and ciliary localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

STAM and Hrs down-regulate ciliary TRP receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

IBA

biological process

ion transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

calcium ion transport

1 reference

1 January 2018

Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

animal behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

mating behavior

IGI

neuronal signal transduction

IC

1 reference

1 January 2018

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

response to hermaphrodite contact

IC

4 references

1 January 2018

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Towards understanding the polycystins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

vulval location

4 references

1 January 2018

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Towards understanding the polycystins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 January 2018

Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

detection of mechanical stimulus

IBA

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

IBA

male mating behavior

1 reference

1 January 2018

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

calcium ion transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9U1S7

1 reference

1 January 2018

Gene Ontology Consortium

reference URL

polycystin cation channel, PKD1/PKD2

has part(s)

1 reference

http://www.ebi.ac.uk/interpro/protein/Q9U1S7

InterPro Release 71.0

reference URL

Identifiers

1 reference

14 December 2018

1 reference

5 December 2018

1 reference

Transporter Classification Database ID

1.A.5.2.4

2 references

Transporter Classification database

13 March 2020

Transporter Classification database