(Q29809321)

http://www.ebi.ac.uk/interpro/protein/P23696

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase family

1 reference

based on heuristic

inferred from protein domain or family

Calcineurin-like phosphoesterase

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

phosphoprotein phosphatase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

protein serine/threonine phosphatase activity

IEA

phosphatase regulator activity

ISS

2 references

1 reference

8 April 2019

Role of protein phosphatase 2A in regulating the visual signaling in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

protein phosphatase type 2A complex

IEA

cell component

1 reference

8 April 2019

Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

3 references

8 April 2019

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

8 April 2019

Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

8 April 2019

Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

microtubule cytoskeleton organization

TAS

biological process

1 reference

8 April 2019

The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of protein phosphorylation

1 reference

8 April 2019

PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

protein dephosphorylation

1 reference

8 April 2019

Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

PP2A regulates autophagy in two alternative ways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

Multiple protein phosphatases are required for mitosis in Drosophila.

chromosome segregation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification

centriole replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of neuroblast proliferation

1 reference

8 April 2019

Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

R7 cell fate commitment

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

response to light stimulus

TAS

1 reference

8 April 2019

Role of protein phosphatase 2A in regulating the visual signaling in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of hippo signaling

1 reference

8 April 2019

Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of smoothened signaling pathway

1 reference

8 April 2019

Sequential phosphorylation of smoothened transduces graded hedgehog signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of insulin receptor signaling pathway

1 reference

8 April 2019

The protein phosphatase PP2A-B' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

wing disc dorsal/ventral pattern formation

1 reference

8 April 2019

PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

regulation of catalytic activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

1 reference

8 April 2019

Multiple protein phosphatases are required for mitosis in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

negative regulation of protein kinase B signaling

1 reference

8 April 2019

The protein phosphatase PP2A-B' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

asymmetric neuroblast division

1 reference

8 April 2019

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

establishment of epithelial cell polarity

1 reference

8 April 2019

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

positive regulation of canonical Wnt signaling pathway

IEP

1 reference

8 April 2019

PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23696

Calcineurin-like phosphoesterase domain, ApaH type

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23696

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

1 reference

stated in

InterPro Release 71.0