(Q29809502)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

ISS

insulin receptor binding

3 references

24 April 2018

24 April 2018

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

24 April 2018

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

insulin-like growth factor receptor binding

IGI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

ISS

insulin receptor binding

4 references

21 June 2018

21 June 2018

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

insulin receptor binding

5 references

8 April 2019

8 April 2019

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

intracellular membrane-bounded organelle

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

primary spermatocyte growth

1 reference

8 April 2019

Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

growth of a germarium-derived egg chamber

1 reference

8 April 2019

Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

determination of adult lifespan

6 references

8 April 2019

Molecular genetics of aging in the fly: is this the end of the beginning?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Genetics of aging in the fruit fly, Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Longevity determination genes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Life span: getting the signal from the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

Mutations in the Drosophila insulin receptor substrate, CHICO, impair olfactory associative learning.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

multicellular organism aging

1 reference

8 April 2019

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

regulation of lipid metabolic process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

regulation of activin receptor signaling pathway

1 reference

8 April 2019

Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

regulation of tube length, open tracheal system

IDA

1 reference

8 April 2019

Genetic control of epithelial tube size in the Drosophila tracheal system.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

multicellular organism growth

1 reference

8 April 2019

Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

positive regulation of multicellular organism growth

5 references

8 April 2019

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

A small issue addressed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

insulin-like growth factor receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

male germ-line stem cell asymmetric division

ISS

1 reference

8 April 2019

Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

positive regulation of immune response

1 reference

8 April 2019

Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

germ-line stem-cell niche homeostasis

1 reference

8 April 2019

Insulin levels control female germline stem cell maintenance via the niche in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

Learning defects in Drosophila growth restricted chico mutants are caused by attenuated adenylyl cyclase activity.

long-term potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

1 reference

8 April 2019

Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

positive regulation of cell population proliferation

1 reference

8 April 2019

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

entry into reproductive diapause

1 reference

14 January 2019

The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

insulin receptor signaling pathway

4 references

24 April 2018

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

24 April 2018

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

24 April 2018

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

24 April 2018

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

cellular response to starvation

IDA

1 reference

8 April 2019

Control of metabolic adaptation to fasting by dILP6-induced insulin signaling in Drosophila oenocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

negative regulation of triglyceride catabolic process

1 reference

8 April 2019

A hormone-dependent module regulating energy balance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

protein kinase B signaling

1 reference

8 April 2019

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

positive regulation of cell size

4 references

8 April 2019

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Tor signalling in bugs, brain and brawn

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

regulation of organ growth

1 reference

8 April 2019

The temporal requirements for insulin signaling during development in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

insulin receptor signaling pathway

5 references

21 June 2018

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

21 June 2018

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9XTN2&geneProductId=UniProtKB:Q9XTN2

insulin receptor signaling pathway

IDA

6 references

8 April 2019

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

phosphatidylinositol phosphate biosynthetic process

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2

negative regulation of entry into reproductive diapause

TAS

1 reference

8 April 2019

The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9XTN2