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(Q29809532)
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Tissue inhibitor of metalloproteases Dmel_CG6281
Protein found in Drosophila melanogaster
Timp
CG6281-PB
Timp-PB
tissue inhibitor of metalloproteases
CG6281 gene product from transcript CG6281-RB
tissue inhibitor of metalloproteinases
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VH14
part of
tissue inhibitor of metalloproteinase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VH14
Tissue inhibitor of metalloproteinases-like, OB-fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VH14
Proteinase inhibitor I35b (TIMP), C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VH14
Netrin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VH14
encoded by
Timp
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VH14
molecular function
protease binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
enzyme inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
metalloendopeptidase inhibitor activity
determination method
IDA
IEA
ISS
4 references
retrieved
24 April 2018
stated in
Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VH14&geneProductId=UniProtKB:Q9VH14
determination method
ISS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VH14&geneProductId=UniProtKB:Q9VH14
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VH14&geneProductId=UniProtKB:Q9VH14
determination method
IEA
retrieved
24 April 2018
stated in
Drosophila TIMP Is a Potent Inhibitor of MMPs and TACE: Similarities in Structure and Function to TIMP-3
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VH14&geneProductId=UniProtKB:Q9VH14
determination method
IDA
zinc ion binding
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
ISS
peptidase inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
metalloendopeptidase inhibitor activity
determination method
IBA
IDA
IEA
ISS
5 references
retrieved
8 April 2019
stated in
Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
retrieved
8 April 2019
stated in
Drosophila TIMP Is a Potent Inhibitor of MMPs and TACE: Similarities in Structure and Function to TIMP-3
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
dendrite
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
extracellular matrix
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
biological process
cell adhesion
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Inflated wings, tissue autolysis and early death in tissue inhibitor of metalloproteinases mutants of Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
ventral cord development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Glia ECM interactions are required to shape the Drosophila nervous system
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
tracheal outgrowth, open tracheal system
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
wing disc morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Tissue remodeling during maturation of the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
response to organic substance
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
negative regulation of peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
negative regulation of endopeptidase activity
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VH14&geneProductId=UniProtKB:Q9VH14
determination method
IEA
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
tracheal pit formation in open tracheal system
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
phototaxis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Inflated wings, tissue autolysis and early death in tissue inhibitor of metalloproteinases mutants of Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
oogenesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VH14
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IEA
imaginal disc-derived wing expansion
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Tissue remodeling during maturation of the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
negative regulation of membrane protein ectodomain proteolysis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
delamination
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Tissue remodeling during maturation of the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
basement membrane organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IMP
negative regulation of endopeptidase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VH14
determination method
IBA
has part(s)
Netrin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VH14
Identifiers
RefSeq protein ID
NP_731461
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41248
UniProt protein ID
Q9VH14
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VH14
Ensembl protein ID
FBpp0081722
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0081722
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