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(Q29809907)
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Mitochondrial DNA helicase Dmel_CG5924
Protein found in Drosophila melanogaster
CG5924 gene product from transcript CG5924-RA
d-mtDNA helicase
mtDNA helicase
mitochondrial DNA helicase
mtDNA-helicase-PA
twinkle
twinkle helicase
mtDNA-helicase
CG5924-PA
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VL76
part of
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VL76
DNA helicase, DnaB-like, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VL76
encoded by
mtDNA-helicase
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VL76
molecular function
DNA helicase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IEA
double-stranded DNA binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The N-terminal domain of the Drosophila mitochondrial replicative DNA helicase contains an iron-sulfur cluster and binds DNA
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IDA
single-stranded DNA binding
determination method
IDA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VL76
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
ISS
retrieved
8 April 2019
stated in
The N-terminal domain of the Drosophila mitochondrial replicative DNA helicase contains an iron-sulfur cluster and binds DNA
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IDA
helicase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VL76
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IEA
ATP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IEA
5'-3' DNA helicase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VL76
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
ISS
2 iron, 2 sulfur cluster binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The N-terminal domain of the Drosophila mitochondrial replicative DNA helicase contains an iron-sulfur cluster and binds DNA
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IDA
cell component
mitochondrion
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IDA
mitochondrial nucleoid
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VL76
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
ISS
biological process
mitochondrial genome maintenance
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IMP
retrieved
8 April 2019
stated in
Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IMP
DNA replication
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IEA
mitochondrial DNA replication
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VL76
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
ISS
DNA duplex unwinding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IEA
protein homooligomerization
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VL76
determination method
IDA
has part(s)
DNA helicase, DnaB-like, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VL76
Identifiers
RefSeq protein ID
NP_609318
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
34307
UniProt protein ID
Q9VL76
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VL76
Ensembl protein ID
FBpp0079501
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0079501
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