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Meiotic W68 Dmel_CG7753
Protein found in Drosophila melanogaster
mei-W68
CG7753 gene product from transcript CG7753-RA
CG7753-PA
mei-W68-PA
meiotic W68
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7KPA5
part of
DNA topoisomerase VI, subunit A
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7KPA5
Spo11/DNA topoisomerase VI subunit A superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7KPA5
Spo11/DNA topoisomerase VI, subunit A, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Topoisomerase 6 subunit A/Spo11, TOPRIM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7KPA5
encoded by
mei-W68
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7KPA5
molecular function
DNA binding
determination method
IBA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
catalytic activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
determination method
IBA
IEA
2 references
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IBA
ATP binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
isomerase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
endodeoxyribonuclease activity, producing 3'-phosphomonoesters
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
metal ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
endodeoxyribonuclease activity, producing 3'-phosphomonoesters
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
cell component
nuclear chromosome
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IBA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
chromosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
biological process
meiotic DNA double-strand break processing
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IDA
DNA catabolic process, endonucleolytic
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
DNA metabolic process
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
DNA topological change
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
reciprocal meiotic recombination
determination method
IMP
TAS
4 references
retrieved
16 July 2018
stated in
The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
TAS
retrieved
16 July 2018
stated in
mei-41 is required for precocious anaphase in Drosophila females
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
TAS
retrieved
16 July 2018
stated in
Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IMP
retrieved
16 July 2018
stated in
Meiotic synapsis in the absence of recombination.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KPA5&geneProductId=UniProtKB:Q7KPA5
determination method
IMP
oocyte karyosome formation
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
The Drosophila hus1 gene is required for homologous recombination repair during meiosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IGI
meiotic DNA double-strand break formation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
early meiotic recombination nodule assembly
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Normal Synaptonemal Complex and Abnormal Recombination Nodules in Two Alleles of the Drosophila Meiotic Mutant mei-W68
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IMP
late meiotic recombination nodule assembly
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Normal Synaptonemal Complex and Abnormal Recombination Nodules in Two Alleles of the Drosophila Meiotic Mutant mei-W68
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IMP
oogenesis
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
Meiotic recombination provokes functional activation of the p53 regulatory network
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IGI
meiosis
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7KPA5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IEA
meiotic DNA double-strand break processing
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
reciprocal meiotic recombination
determination method
IBA
IMP
TAS
5 references
retrieved
9 May 2019
stated in
The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
TAS
retrieved
9 May 2019
stated in
mei-41 is required for precocious anaphase in Drosophila females
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
TAS
retrieved
9 May 2019
stated in
Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IMP
retrieved
9 May 2019
stated in
Meiotic synapsis in the absence of recombination.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KPA5
determination method
IBA
has part(s)
Topoisomerase 6 subunit A/Spo11, TOPRIM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7KPA5
Spo11/DNA topoisomerase VI, subunit A, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7KPA5
Identifiers
RefSeq protein ID
NP_995901
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
2768853
UniProt protein ID
Q7KPA5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7KPA5
Ensembl protein ID
FBpp0085657
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0085657
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