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Thioredoxin peroxidase 2 Dmel_CG1274
Protein found in Drosophila melanogaster
CG1274-PB
jafrac2
CG1274-PC
peroxiredoxin 4
Jafrac2-PA
CG1274-PA
thioredoxin peroxidase
Jafrac2-PC
peroxiredoxin 4156
CG1274 gene product from transcript CG1274-RA
thioredoxin peroxidase 2
Jafrac2-PB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Q4
part of
Thioredoxin-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Q4
Peroxiredoxin, AhpC-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Q4
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, protein family
1 reference
based on heuristic
inferred from protein domain or family
Thioredoxin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Peroxiredoxin, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Q4
encoded by
Jafrac2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Q4
molecular function
peroxidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V3Q4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IPI
thioredoxin peroxidase activity
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The peroxiredoxin gene family in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
antioxidant activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
oxidoreductase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V3Q4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
peroxiredoxin activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
thioredoxin peroxidase activity
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
The peroxiredoxin gene family in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
cell component
extracellular region
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The peroxiredoxin gene family in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
extracellular space
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
endoplasmic reticulum
determination method
IDA
2 references
retrieved
1 January 2018
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
1 January 2018
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
endomembrane system
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Mapping organelle proteins and protein complexes in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
endoplasmic reticulum
determination method
IBA
IDA
3 references
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
cytosol
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
endomembrane system
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Mapping organelle proteins and protein complexes in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
HDA
biological process
cellular response to DNA damage stimulus
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
A network of conserved damage survival pathways revealed by a genomic RNAi screen.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IMP
response to oxidative stress
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IMP
defense response to bacterium
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
hydrogen peroxide catabolic process
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The peroxiredoxin gene family in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
cell redox homeostasis
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3Q4&geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
positive regulation of receptor signaling pathway via JAK-STAT
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IGI
cellular response to cold
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
apoptotic signaling pathway
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IMP
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IGI
cellular oxidant detoxification
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IMP
response to oxidative stress
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
hydrogen peroxide catabolic process
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
The peroxiredoxin gene family in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
cell redox homeostasis
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3Q4
determination method
IBA
has part(s)
Peroxiredoxin, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Q4
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Q4
Thioredoxin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3Q4
Identifiers
RefSeq protein ID
NP_001261350
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
53577
NP_525002
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
53577
NP_728793
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
53577
UniProt protein ID
Q9V3Q4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3Q4
Ensembl protein ID
FBpp0072853
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0072853
FBpp0072852
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0072852
FBpp0304422
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0304422
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