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(Q29810590)
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Polycomb Dmel_CG32443
Protein found in Drosophila melanogaster
Pc
Pc-PA
CG32443 gene product from transcript CG32443-RA
polycomb
CG32443-PA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P26017
part of
Chromo-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Chromo domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Chromo/chromo shadow domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Chromo domain subgroup, protein family
1 reference
based on heuristic
inferred from protein domain or family
Chromo domain, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
CBX family C-terminal motif, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P26017
encoded by
Pc
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P26017
molecular function
chromatin binding
determination method
IDA
2 references
retrieved
1 January 2018
stated in
Polycomb preferentially targets stalled promoters of coding and noncoding transcripts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
retrieved
1 January 2018
stated in
Chromosomal distribution of PcG proteins during Drosophila development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
methylated histone binding
determination method
IDA
TAS
2 references
retrieved
1 January 2018
stated in
Histone lysine methylation: a signature for chromatin function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
TAS
retrieved
1 January 2018
stated in
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
cell component
chromatin
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
nucleus
determination method
IDA
IEA
3 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P26017
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IEA
retrieved
1 January 2018
stated in
RNAi components are required for nuclear clustering of Polycomb group response elements.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
intercalary heterochromatin
determination method
NAS
1 reference
retrieved
1 January 2018
stated in
Intercalary heterochromatin and genetic silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
NAS
nucleolus
determination method
IDA
2 references
retrieved
1 January 2018
stated in
Sequential changes at differentiation gene promoters as they become active in a stem cell lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
retrieved
1 January 2018
stated in
Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
PRC1 complex
determination method
IDA
TAS
4 references
retrieved
1 January 2018
stated in
Anything else but GAGA: a nonhistone protein complex reshapes chromatin structure
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
TAS
retrieved
1 January 2018
stated in
Division of labor in polycomb group repression
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
TAS
retrieved
1 January 2018
stated in
NuRD and SIN3 histone deacetylase complexes in development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
TAS
retrieved
1 January 2018
stated in
Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IDA
biological process
regulation of transcription, DNA-templated
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
specification of segmental identity, abdomen
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Allocation and specification of the genital disc precursor cells in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
ventral cord development
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
negative regulation of gene expression
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Repression of Abd-B by Polycomb is critical for cell identity maintenance in adult Drosophila testis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
neuron remodeling
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Steroid hormone-dependent transformation of polyhomeotic mutant neurons in the Drosophila brain.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
neurogenesis
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
syncytial blastoderm mitotic cell cycle
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Polycomb group mutants exhibit mitotic defects in syncytial cell cycles of Drosophila embryos.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
wound healing
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
negative regulation of transcription, DNA-templated
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Polycomb preferentially targets stalled promoters of coding and noncoding transcripts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
negative regulation of response to gamma radiation
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Epigenetic blocking of an enhancer region controls irradiation-induced proapoptotic gene expression in Drosophila embryos
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26017&geneProductId=UniProtKB:P26017
determination method
IMP
has part(s)
CBX family C-terminal motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Chromo domain subgroup
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Chromo domain, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Chromo/chromo shadow domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Chromo domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P26017
Identifiers
RefSeq protein ID
NP_524199
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40358
UniProt protein ID
P26017
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P26017
Ensembl protein ID
FBpp0078059
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0078059
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