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PR/SET domain containing protein 7 Dmel_CG3307
Protein found in Drosophila melanogaster
PR-Set7-PB
PR-Set7-PA
pr-set7
CG3307-PA
PR/SET domain containing protein 7
SET domain containing 8
PR-Set7-PD
CG3307-PD
CG3307-PB
CG3307 gene product from transcript CG3307-RB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFK6
part of
Class V SAM-dependent methyltransferases
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFK6
SET domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFK6
encoded by
PR-Set7
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFK6
molecular function
methyltransferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
histone-lysine N-methyltransferase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
histone methyltransferase activity (H4-K20 specific)
determination method
IMP
TAS
4 references
retrieved
8 April 2019
stated in
Intercalary heterochromatin and genetic silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
TAS
retrieved
8 April 2019
stated in
Histone lysine methylation: a signature for chromatin function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
TAS
retrieved
8 April 2019
stated in
PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
retrieved
8 April 2019
stated in
Preferential dimethylation of histone H4 lysine 20 by Suv4-20
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
cell component
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
chromosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
polytene chromosome
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IDA
biological process
DNA damage checkpoint signaling
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IDA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VFK6&geneProductId=UniProtKB:Q9VFK6
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VFK6&geneProductId=UniProtKB:Q9VFK6
determination method
IEA
cell cycle
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
histone methylation
determination method
IMP
TAS
4 references
retrieved
8 April 2019
stated in
Histone lysine methylation: a signature for chromatin function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
TAS
retrieved
8 April 2019
stated in
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
retrieved
8 April 2019
stated in
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
retrieved
8 April 2019
stated in
PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
chromosome condensation
determination method
IDA
IGI
2 references
retrieved
8 April 2019
stated in
Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IGI
retrieved
8 April 2019
stated in
Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IDA
methylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
histone H4-K20 monomethylation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Preferential dimethylation of histone H4 lysine 20 by Suv4-20
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IMP
negative regulation of histone acetylation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Histone lysine methylation: a signature for chromatin function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
TAS
cell division
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
chromatin organization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFK6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFK6
determination method
IEA
has part(s)
SET domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFK6
Identifiers
RefSeq protein ID
NP_001247100
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41743
NP_650354
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41743
NP_731900
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41743
UniProt protein ID
Q9VFK6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFK6
Ensembl protein ID
FBpp0301702
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0301702
FBpp0082389
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0082389
FBpp0082388
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0082388
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