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(Q29811398)
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Ced-12 Dmel_CG5336
Protein found in Drosophila melanogaster
Ced-12
engulfment and cell motility
CG5336 gene product from transcript CG5336-RA
Ced-12-PA
elmo
CG5336-PA
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VKB2
part of
Engulfment and cell motility protein 3
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
Armadillo-type fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
ELMO domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Domain of unknown function DUF3361, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VKB2
encoded by
Ced-12
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VKB2
molecular function
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IPI
retrieved
8 April 2019
stated in
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IPI
cell component
nucleus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IDA
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IDA
biological process
actin filament organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
border follicle cell migration
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
retrieved
8 April 2019
stated in
Two distinct modes of guidance signalling during collective migration of border cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
central nervous system development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
myoblast fusion
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
retrieved
8 April 2019
stated in
Mechanical tension drives cell membrane fusion
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
muscle attachment
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IGI
cell migration
determination method
IEA
IGI
2 references
retrieved
8 April 2019
stated in
The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IEA
activation of GTPase activity
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IGI
positive regulation of JNK cascade
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IDA
imaginal disc fusion, thorax closure
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
vascular endothelial growth factor receptor signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VKB2
determination method
IMP
has part(s)
Domain of unknown function DUF3361
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
ELMO domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VKB2
Identifiers
RefSeq protein ID
NP_609548
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
34633
UniProt protein ID
Q9VKB2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VKB2
Ensembl protein ID
FBpp0079912
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0079912
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