Wikidata

(Q29811410)

English

Spatzle Dmel_CG6134

Protein found in Drosophila melanogaster

  • CG6134-PL
  • spazle
  • spz-PB
  • spz-PK
  • CG6134-PA
  • spz-PL
  • CG6134-PJ
  • spz-PJ
  • CG6134-PC
  • spz-PC
  • CG6134-PD
  • spz-PA
  • spaetzle
  • spaztle
  • spatzle
  • protein spaetzle precursor
  • CG6134-PB
  • spz
  • spz-PD
  • CG6134-PI
  • CG6134-PK
  • spz-PI
  • CG6134 gene product from transcript CG6134-RL
In more languages

Statements

named after
spätzle
0 references
molecular function
Toll binding
determination method
IGI
IPI
NAS
TAS
8 references
retrieved
27 February 2018
stated in
Toll gets tied in a knot
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
27 February 2018
stated in
The immune response of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
27 February 2018
stated in
Role of Toll-like receptors in pathogen recognition.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
27 February 2018
stated in
Conservation and divergence in molecular mechanisms of axis formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
27 February 2018
stated in
The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
27 February 2018
stated in
Toll we meet again....
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
27 February 2018
stated in
Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
27 February 2018
stated in
A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IGI
Toll binding
determination method
IBA
IGI
IPI
NAS
TAS
9 references
retrieved
10 September 2018
stated in
The immune response of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Toll gets tied in a knot
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Conservation and divergence in molecular mechanisms of axis formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Role of Toll-like receptors in pathogen recognition.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Toll we meet again....
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
10 September 2018
stated in
The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
10 September 2018
stated in
Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
10 September 2018
stated in
A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IGI
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IBA
Toll binding
determination method
IBA
IDA
IPI
6 references
retrieved
8 April 2019
stated in
Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
8 April 2019
stated in
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
8 April 2019
stated in
Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IPI
retrieved
8 April 2019
stated in
Multimerization and interaction of Toll and Spätzle in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IBA
cell component
biological process
Toll signaling pathway
determination method
IDA
NAS
TAS
9 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Dorsal gradient networks in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Conservation and divergence in molecular mechanisms of axis formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
The evolution and genetics of innate immunity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
Role of Toll-like receptors in pathogen recognition.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
10 September 2018
stated in
The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo
GOA
curator
UniProt
UniProt protein ID
P48607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
10 September 2018
stated in
Toll we meet again....
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
10 September 2018
stated in
The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
10 September 2018
stated in
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48607&geneProductId=UniProtKB:P48607
determination method
IDA
Toll signaling pathway
determination method
IDA
IGI
IMP
NAS
TAS
15 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
TAS
retrieved
8 April 2019
stated in
The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo
GOA
curator
UniProt
UniProt protein ID
P48607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
NAS
retrieved
8 April 2019
stated in
A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
Spätzle-Processing Enzyme-independent Activation of the Toll Pathway in Drosophila Innate Immunity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
Toll-related receptors and the control of antimicrobial peptide expression in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IMP
retrieved
8 April 2019
stated in
A serpin regulates dorsal-ventral axis formation in the Drosophila embryo.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IGI
retrieved
8 April 2019
stated in
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IDA
retrieved
8 April 2019
stated in
Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IDA
retrieved
8 April 2019
stated in
Cactus protein degradation mediates Drosophila dorsal-ventral signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IDA
retrieved
8 April 2019
stated in
Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48607
determination method
IDA

Identifiers

 
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