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Smg6 Dmel_CG6369
Protein found in Drosophila melanogaster
CG6369 gene product from transcript CG6369-RA
CG6369-PA
Smg6-PA
Smg6
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VBZ6
part of
Tetratricopeptide-like helical domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VBZ6
PIN-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VBZ6
DNA/RNA-binding domain, Est1-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
PIN domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VBZ6
encoded by
Smg6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VBZ6
molecular function
endoribonuclease activity
determination method
ISS
1 reference
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VBZ6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
ISS
ribonuclease activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
telomeric DNA binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
ribonucleoprotein complex binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
telomerase RNA binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
ribonuclease activity
determination method
IBA
IDA
2 references
retrieved
10 September 2018
stated in
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
endoribonuclease activity
determination method
IBA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VBZ6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
ISS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
cell component
telomerase holoenzyme complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
cytoplasm
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
cytosol
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VBZ6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
ISS
biological process
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
determination method
IDA
IMP
4 references
retrieved
16 July 2018
stated in
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
16 July 2018
stated in
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
16 July 2018
stated in
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
16 July 2018
stated in
The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
mRNA export from nucleus
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
telomere maintenance via telomerase
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
neuromuscular synaptic transmission
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
RNA interference
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
gene silencing by miRNA
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
regulation of RNA stability
determination method
IMP
1 reference
retrieved
16 July 2018
stated in
Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VBZ6&geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
synapse organization
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
RNA phosphodiester bond hydrolysis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IEA
RNA phosphodiester bond hydrolysis, endonucleolytic
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IEA
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
determination method
IBA
IDA
IMP
5 references
retrieved
8 April 2019
stated in
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
8 April 2019
stated in
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
8 April 2019
stated in
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
8 April 2019
stated in
The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
regulation of RNA stability
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
regulation of telomere maintenance via telomerase
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VBZ6
determination method
IBA
has part(s)
DNA/RNA-binding domain, Est1-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VBZ6
PIN domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VBZ6
Identifiers
RefSeq protein ID
NP_651321
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
42994
UniProt protein ID
Q9VBZ6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VBZ6
Ensembl protein ID
FBpp0084171
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0084171
Sitelinks
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Multilingual sites
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