Wikidata

(Q29813249)

English

Hippo Dmel_CG11228

Protein found in Drosophila melanogaster

  • CG11228-PA
  • hippo
  • hpo-PB
  • hippo kinase
  • MST
  • hpo-PA
  • hpo
  • CG11228 gene product from transcript CG11228-RB
  • CG11228-PB
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein serine/threonine kinase activity
determination method or standard
IDA
IEA
8 references
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IEA
retrieved
16 July 2018
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
A protein interaction map of Drosophila melanogaster
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
retrieved
8 April 2019
stated in
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IPI
protein serine/threonine kinase activity
determination method or standard
IBA
IDA
IEA
9 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IEA
retrieved
8 April 2019
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IBA
cell component
biological process
hippo signaling
determination method or standard
IDA
IGI
IMP
TAS
9 references
retrieved
16 July 2018
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
TAS
retrieved
16 July 2018
stated in
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IMP
retrieved
16 July 2018
stated in
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IMP
retrieved
16 July 2018
stated in
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IGI
retrieved
16 July 2018
stated in
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IGI
retrieved
16 July 2018
stated in
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
16 July 2018
stated in
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
hippo signaling
determination method or standard
IBA
IDA
IGI
IMP
TAS
10 references
retrieved
8 April 2019
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
UniProt
UniProt protein ID
Q8T0S6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
TAS
retrieved
8 April 2019
stated in
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IMP
retrieved
8 April 2019
stated in
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IMP
retrieved
8 April 2019
stated in
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IGI
retrieved
8 April 2019
stated in
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IGI
retrieved
8 April 2019
stated in
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6
determination method or standard
IBA

Identifiers

 
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