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(Q29814597)
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English
Derailed 2 Dmel_CG3915
Protein found in Drosophila melanogaster
doughnut-like
CG3915-PB
CG3915-PC
derailed 2
Drl-2
CG3915 gene product from transcript CG3915-RC
Drl-2-PB
Drl-2-PC
derailed-2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7JQT0
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
WIF domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
WIF domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Tyrosine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7JQT0
encoded by
Drl-2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7JQT0
molecular function
protein kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
protein tyrosine kinase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
ISS
ATP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7JQT0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
Wnt-protein binding
determination method
IPI
1 reference
retrieved
21 June 2018
stated in
Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IPI
protein heterodimerization activity
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IPI
receptor tyrosine kinase
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
transmembrane signaling receptor activity
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
Wnt-protein binding
determination method
IBA
IPI
2 references
retrieved
8 April 2019
stated in
Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
transmembrane receptor protein tyrosine kinase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
cell component
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7JQT0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7JQT0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
receptor complex
determination method
IDA
1 reference
retrieved
21 June 2018
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IDA
cytoplasm
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
integral component of plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
receptor complex
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
biological process
protein phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
salivary gland morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IMP
motor neuron axon guidance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Wnt4 is a local repulsive cue that determines synaptic target specificity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IMP
Wnt signaling pathway
determination method
TAS
1 reference
retrieved
21 June 2018
stated in
Ryks: new partners for Wnts in the developing and regenerating nervous system
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
TAS
synaptic target inhibition
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Wnt4 is a local repulsive cue that determines synaptic target specificity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IMP
chemorepulsion of axon
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IMP
peptidyl-tyrosine phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IEA
negative regulation of signal transduction
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
Wnt signaling pathway
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Ryks: new partners for Wnts in the developing and regenerating nervous system
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
cell differentiation
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
negative regulation of apoptotic process
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
positive regulation of ERK1 and ERK2 cascade
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7JQT0&geneProductId=UniProtKB:Q7JQT0
determination method
IBA
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
nervous system development
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
axonogenesis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7JQT0
determination method
IBA
has part(s)
tyrosine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
serine-threonine/tyrosine-protein kinase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
WIF domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7JQT0
Identifiers
RefSeq protein ID
NP_001286371
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36436
NP_610835
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36436
UniProt protein ID
Q7JQT0
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7JQT0
Ensembl protein ID
FBpp0308795
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0308795
FBpp0086907
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086907
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