(Q29814611)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

nuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

endonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

protein binding

6 references

1 January 2018

Structural insights into the sequence-specific recognition of Piwi by Drosophila Papi.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Panoramix enforces piRNA-dependent cotranscriptional silencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

The role of PIWI and the miRNA machinery in Drosophila germline determination.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

cell component

chromatin

1 reference

1 January 2018

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

euchromatin

1 reference

1 January 2018

Drosophila PIWI associates with chromatin and interacts directly with HP1a

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

nucleus

RNA interference: traveling in the cell and gaining functions?

9 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

1 January 2018

Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

The cochaperone shutdown defines a group of biogenesis factors essential for all piRNA populations in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

RNAi components are required for nuclear clustering of Polycomb group response elements.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

nucleoplasm

The stem-cell niche theory: lessons from flies

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

1 January 2018

piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

polytene chromosome

1 reference

1 January 2018

Drosophila PIWI associates with chromatin and interacts directly with HP1a

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

3 references

1 January 2018

1 January 2018

Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

cytosol

HDA

1 reference

1 January 2018

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

HDA

chromocenter

1 reference

1 January 2018

Drosophila PIWI associates with chromatin and interacts directly with HP1a

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

protein-containing complex

1 reference

1 January 2018

Structural insights into the sequence-specific recognition of Piwi by Drosophila Papi.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

Yb body

1 reference

1 January 2018

A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

negative regulation of transposition, DNA-mediated

biological process

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

pole cell formation

1 reference

1 January 2018

The role of PIWI and the miRNA machinery in Drosophila germline determination.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

spermatogenesis

1 reference

1 January 2018

Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

germarium-derived oocyte fate determination

1 reference

1 January 2018

Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

negative regulation of transposition

3 references

1 January 2018

Separation of stem cell maintenance and transposon silencing functions of Piwi protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

RNA interference

1 reference

1 January 2018

RNA interference: traveling in the cell and gaining functions?

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

posttranscriptional gene silencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

1 January 2018

negative regulation of BMP signaling pathway

1 reference

1 January 2018

Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

germ-line stem cell population maintenance

ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 January 2018

piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

germ-line stem cell division

1 reference

1 January 2018

The stem-cell niche theory: lessons from flies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

female germ-line stem cell asymmetric division

1 reference

1 January 2018

A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

male germ-line stem cell asymmetric division

1 reference

1 January 2018

A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

oogenesis

1 reference

1 January 2018

Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

1 reference

1 January 2018

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

nucleic acid phosphodiester bond hydrolysis

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

positive regulation of DNA methylation-dependent heterochromatin assembly

1 reference

1 January 2018

Panoramix enforces piRNA-dependent cotranscriptional silencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VKM1&geneProductId=UniProtKB:Q9VKM1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VKM1

Piwi domain

1 reference

InterPro Release 71.0