(Q29814666)

Death-like domain superfamily

1 reference

Death domain, protein family

1 reference

Pelle, death domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

protein kinase activity

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

protein serine/threonine kinase activity

IDA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

7 references

8 April 2019

Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

A heterotrimeric death domain complex in Toll signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Three-dimensional structure of a complex between the death domains of Pelle and Tube

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

protein domain specific binding

1 reference

8 April 2019

Three-dimensional structure of a complex between the death domains of Pelle and Tube

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

IPI

protein kinase activity

3 references

8 April 2019

8 April 2019

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

4 references

27 March 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

27 March 2018

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

27 March 2018

Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

5 references

10 September 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

Protein kinases and phosphatases in the Drosophila genome

IBA

biological process

protein phosphorylation

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

Three-dimensional structure of a complex between the death domains of Pelle and Tube

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

1 reference

10 September 2018

The antimicrobial host defense of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

zygotic specification of dorsal/ventral axis

1 reference

8 April 2019

Information for the dorsal--ventral pattern of the Drosophila embryo is stored as maternal mRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

larval somatic muscle development

1 reference

8 April 2019

The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

Three-dimensional structure of a complex between the death domains of Pelle and Tube

Toll signaling pathway

5 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

A universal role for MyD88 in TLR/IL-1R-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

Drosophila: the genetics of innate immune recognition and response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

The immune response of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

10 September 2018

The evolution and genetics of innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

1 reference

10 September 2018

Fly immunity: great expectations

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

antifungal humoral response

1 reference

10 September 2018

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

regulation of proteolysis

1 reference

1 January 2018

The immune response of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis

hemocyte proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

intracellular signal transduction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

Three-dimensional structure of a complex between the death domains of Pelle and Tube

IBA

innate immune response

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

protein autophosphorylation

1 reference

8 April 2019

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

determination of dorsal/ventral asymmetry

IDA

1 reference

8 April 2019

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

1 reference

10 September 2018

The antimicrobial host defense of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05652&geneProductId=UniProtKB:Q05652

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

protein phosphorylation

3 references

8 April 2019

8 April 2019

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

Three-dimensional structure of a complex between the death domains of Pelle and Tube

IDA

Toll signaling pathway

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

A heterotrimeric death domain complex in Toll signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Endocytic pathway is required for Drosophila Toll innate immune signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Drosophila MyD88 is an adapter in the Toll signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

8 April 2019

Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

dorsal/ventral pattern formation

IGI

IGI

antifungal innate immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05652

has part(s)

protein kinase domain

1 reference

Death domain

1 reference

protein kinase, ATP binding site

1 reference

serine/threonine-protein kinase, active site

1 reference

Pelle, death domain

1 reference