(Q29814708)

WD40-repeat-containing domain superfamily

1 reference

LIS1, N-terminal

1 reference

WD40/YVTN repeat-like-containing domain superfamily

1 reference

LIS1 homology motif, protein family

1 reference

WD40 repeat, protein family

1 reference

WD40 repeat, conserved site, protein family

1 reference

G-protein beta WD-40 repeat, protein family

1 reference

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

dynein complex binding

Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome

IPI

ISS

dynein complex binding

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

16 July 2018

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

microtubule plus-end binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome

dynein complex binding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

chromosome, centromeric region

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

16 July 2018

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

16 July 2018

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

microtubule organizing center

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

kinetochore microtubule

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

spindle pole centrosome

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

microtubule associated complex

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

cytoplasmic microtubule

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

3 references

9 May 2019

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

establishment of mitotic spindle orientation

biological process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

intracellular protein transport

1 reference

9 May 2019

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

microtubule-based movement

1 reference

9 May 2019

Flying through the drosophila cytoskeletal genome.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

mitotic cell cycle checkpoint signaling

1 reference

16 July 2018

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNS3&geneProductId=UniProtKB:Q7KNS3

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

germarium-derived oocyte fate determination

3 references

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

border follicle cell migration

1 reference

9 May 2019

Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

cytoplasmic transport, nurse cell to oocyte

1 reference

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

oocyte nucleus migration involved in oocyte dorsal/ventral axis specification

1 reference

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

nervous system development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

axo-dendritic transport

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

3 references

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

intracellular mRNA localization

3 references

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

transport along microtubule

1 reference

9 May 2019

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

stem cell population maintenance

1 reference

9 May 2019

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

nuclear migration along microtubule

1 reference

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

regulation of BMP signaling pathway

1 reference

8 April 2019

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

germarium-derived oocyte differentiation

oocyte fate determination

1 reference

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

ovarian fusome organization

1 reference

9 May 2019

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

protein localization to kinetochore

1 reference

9 May 2019

Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

New dystrophin/dystroglycan interactors control neuron behavior in Drosophila eye.

rhabdomere development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

regulation of translation by machinery localization

1 reference

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

muscle cell cellular homeostasis

dorsal appendage formation

1 reference

9 May 2019

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

vesicle transport along microtubule

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

female germ-line cyst formation

1 reference

9 May 2019

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

germarium-derived cystoblast division

1 reference

9 May 2019

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

3 references

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

regulation of dendrite morphogenesis

1 reference

9 May 2019

Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

centrosome separation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

kinetochore organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis

centrosome localization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

clathrin-dependent endocytosis involved in vitellogenesis

1 reference

9 May 2019

Efficient Endocytic Uptake and Maturation in Drosophila Oocytes Requires Dynamitin/p50.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

photoreceptor cell axon guidance

1 reference

9 May 2019

New dystrophin/dystroglycan interactors control neuron behavior in Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

positive regulation of axonogenesis

1 reference

9 May 2019

Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

microtubule-based process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

retrograde axonal transport

3 references

9 May 2019

Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

microtubule organizing center organization

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3

positive regulation of BMP signaling pathway

1 reference

9 May 2019

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNS3