(Q29815000)

English

Shifted Dmel_CG3135

Protein found in Drosophila melanogaster

shf
shf-PA
CG3135 gene product from transcript CG3135-RC
shf-PB
shifted
CG3135-PA
shf-PD
CG3135-PD
CG3135-PB
CG3135-PC
shf-PC
WNT inhibitory factor

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Statements

1 reference

25 May 2022

WIF domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3W5

WIF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

The WIF domain of the human and Drosophila Wif-1 secreted factors confers specificity for Wnt or Hedgehog.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

1 reference

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

determination method

IDA

biological process

smoothened signaling pathway

3 references

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

determination method

IGI

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

determination method

IEA

synaptic target recognition

1 reference

8 April 2019

A screen of cell-surface molecules identifies leucine-rich repeat proteins as key mediators of synaptic target selection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

determination method

IMP

regulation of smoothened signaling pathway

1 reference

7 November 2018

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3W5&geneProductId=UniProtKB:Q9W3W5

determination method

IMP

Wnt signaling pathway

determination method

IMP

positive regulation of smoothened signaling pathway

6 references

8 April 2019

The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

Balancing Hedgehog, a retention and release equilibrium given by Dally, Ihog, Boi and shifted/DmWif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

The role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

8 April 2019

The WIF domain of the human and Drosophila Wif-1 secreted factors confers specificity for Wnt or Hedgehog.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

determination method

IMP

protein stabilization

1 reference

8 April 2019

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3W5

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3W5

EGF-like, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3W5

WIF domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3W5

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

(Q29815000)

Shifted Dmel_CG3135

Statements

Identifiers

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