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(Q29815007)
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Doughnut on 2 Dmel_CG17559
Protein found in Drosophila melanogaster
CG17559 gene product from transcript CG17559-RB
CG17559-PB
dnt-PA
dnt-PB
CG17559-PA
doughnut
doughnut on 2
dnt
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V422
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
WIF domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
WIF domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Tyrosine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V422
encoded by
dnt
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V422
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
protein kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
protein tyrosine kinase activity
determination method
IKR
1 reference
retrieved
8 April 2019
stated in
Revelations of the RYK receptor
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IKR
ATP binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
protein heterodimerization activity
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IPI
receptor tyrosine kinase
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
transmembrane signaling receptor activity
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
Wnt-protein binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
transmembrane receptor protein tyrosine kinase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
cell component
plasma membrane
determination method
IEA
ISS
2 references
retrieved
8 April 2019
stated in
A Drosophila derailed homolog, doughnut, expressed in invaginating cells during embryogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
receptor complex
determination method
IDA
1 reference
retrieved
21 June 2018
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IDA
cytoplasm
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
integral component of plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
receptor complex
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
biological process
protein phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
signal transduction
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
axon guidance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IMP
salivary gland morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IMP
muscle attachment
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IMP
determination of muscle attachment site
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
WNT5 interacts with the Ryk receptors doughnut and derailed to mediate muscle attachment site selection in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IMP
phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V422
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
peptidyl-tyrosine phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IEA
negative regulation of signal transduction
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
Wnt signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
cell differentiation
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
negative regulation of apoptotic process
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
positive regulation of ERK1 and ERK2 cascade
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V422&geneProductId=UniProtKB:Q9V422
determination method
IBA
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
nervous system development
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
axonogenesis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V422
determination method
IBA
has part(s)
tyrosine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
serine-threonine/tyrosine-protein kinase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
WIF domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V422
Identifiers
RefSeq protein ID
NP_001260567
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35207
NP_477341
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35207
UniProt protein ID
Q9V422
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V422
Ensembl protein ID
FBpp0307787
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0307787
FBpp0080765
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0080765
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