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(Q29815770)
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Cyclin-dependent kinase 4 Dmel_CG5072
Protein found in Drosophila melanogaster
CG5072-PC
cyclin-dependent kinase 4
Cdk4-PD
Cdk4
CG5072-PD
CG5072-PE
CG5072-PA
Cdk4-PA
CG5072-PB
Cyclin-dependent kinase 4/6
Cdk4-PE
protein kinase-like 53C
Cdk4-PC
Cdk4-PB
CG5072 gene product from transcript CG5072-RC
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7K306
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7K306
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7K306
encoded by
Cdk4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7K306
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
protein kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
cyclin-dependent protein serine/threonine kinase activity
determination method
IBA
IEA
ISS
3 references
retrieved
8 April 2019
stated in
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IBA
ATP binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
cyclin binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IPI
retrieved
8 April 2019
stated in
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IPI
protein serine/threonine kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
cell component
cyclin-dependent protein kinase holoenzyme complex
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
nucleus
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IBA
cytoplasm
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
biological process
mitochondrion organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
blastoderm segmentation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
open tracheal system development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
cell population proliferation
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
The Drosophila cyclin D-Cdk4 complex promotes cellular growth
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IGI
positive regulation of cell population proliferation
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
response to organic substance
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
regulation of G2/M transition of mitotic cell cycle
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
regulation of gene expression
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7K306
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
positive regulation of receptor signaling pathway via JAK-STAT
determination method
IGI
IMP
IPI
3 references
retrieved
8 April 2019
stated in
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IPI
retrieved
8 April 2019
stated in
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
retrieved
8 April 2019
stated in
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IGI
positive regulation of TORC1 signaling
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
retrieved
8 April 2019
stated in
Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IGI
G1/S transition of mitotic cell cycle
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K306&geneProductId=UniProtKB:Q7K306
determination method
IBA
protein phosphorylation
determination method
IBA
IEA
ISS
3 references
retrieved
8 April 2019
stated in
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IBA
positive regulation of cell growth
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
retrieved
8 April 2019
stated in
The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IMP
regulation of cell cycle
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K306
determination method
IEA
has part(s)
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7K306
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7K306
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7K306
Identifiers
RefSeq protein ID
NP_001286493
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36854
NP_001286494
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36854
NP_477196
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36854
NP_725594
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36854
NP_725595
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36854
UniProt protein ID
Q7K306
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7K306
Ensembl protein ID
FBpp0311495
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0311495
FBpp0086249
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086249
FBpp0086251
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086251
FBpp0309069
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0309069
FBpp0086250
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086250
Sitelinks
Wikipedia
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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