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Minichromosome maintenance 2 Dmel_CG7538
Protein found in Drosophila melanogaster
Mcm2
Mcm2-PA
CG7538-PA
CG7538 gene product from transcript CG7538-RA
minichromosome maintenance 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P49735
part of
Nucleic acid-binding, OB-fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
DNA replication licensing factor Mcm2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
MCM N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
MCM OB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
MCM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Mini-chromosome maintenance, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P49735
encoded by
Mcm2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P49735
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
DNA binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
helicase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
protein binding
determination method
IPI
4 references
retrieved
9 May 2019
stated in
The structural basis for MCM2-7 helicase activation by GINS and Cdc45.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IPI
retrieved
9 May 2019
stated in
Nearest neighbour analysis of MCM protein complexes in Drosophila melanogaster
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IPI
retrieved
9 May 2019
stated in
Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IPI
retrieved
9 May 2019
stated in
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IPI
ATP binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
3'-5' DNA helicase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IDA
metal ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
DNA replication origin binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
single-stranded DNA binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
single-stranded DNA helicase activity
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
3'-5' DNA helicase activity
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
cell component
nucleus
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
MCM complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
nucleus
determination method
IBA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
MCM complex
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
biological process
DNA replication
determination method
IEA
TAS
3 references
retrieved
9 May 2019
stated in
Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
DNA replication initiation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
cell cycle
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
chromosome condensation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IMP
DNA duplex unwinding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
cell division
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P49735
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
negative regulation of DNA helicase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IEA
double-strand break repair via break-induced replication
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
pre-replicative complex assembly involved in nuclear cell cycle DNA replication
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
DNA unwinding involved in DNA replication
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
mitotic DNA replication initiation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49735
determination method
IBA
has part(s)
MCM OB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
Mini-chromosome maintenance, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
MCM N-terminal domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
MCM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P49735
Identifiers
RefSeq protein ID
NP_477121
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40973
UniProt protein ID
P49735
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P49735
Ensembl protein ID
FBpp0081317
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0081317
Sitelinks
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Multilingual sites
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