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DP transcription factor Dmel_CG4654
Protein found in Drosophila melanogaster
Dp
CG4654-PC
lethal(2)49Fk
dimerization partner
Dp-PB
CG4654 gene product from transcript CG4654-RA
Dp-PA
CG4654-PB
DP transcription factor
CG4654-PA
Dp-PC
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q24318
part of
Winged helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
Transcription factor DP
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
Winged helix-like DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
E2F-DP heterodimerization region
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
Transcription factor DP, C-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
E2F/DP family, winged-helix DNA-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Transcription factor DP, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q24318
encoded by
Dp
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q24318
molecular function
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IPI
1 reference
retrieved
16 July 2018
stated in
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IPI
DNA binding
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q24318
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
retrieved
8 April 2019
stated in
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IDA
DNA-binding transcription factor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
retrieved
8 April 2019
stated in
Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
retrieved
8 April 2019
stated in
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
transcription factor binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
retrieved
8 April 2019
stated in
Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
sequence-specific DNA binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IBA
IPI
2 references
retrieved
8 April 2019
stated in
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IBA
cell component
nucleus
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q24318
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IEA
transcription regulator complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
Myb complex
determination method
IDA
2 references
retrieved
8 April 2019
stated in
Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IDA
retrieved
8 April 2019
stated in
Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IDA
Rb-E2F complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IDA
nucleus
determination method
IBA
IEA
2 references
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q24318
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IEA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IBA
nucleus
determination method
HDA
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q24318
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IBA
retrieved
8 April 2019
stated in
A genome-wide resource for the analysis of protein localisation in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
HDA
biological process
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q24318
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
cell cycle
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IEA
endomitotic cell cycle
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
TAS
eggshell chorion gene amplification
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
TAS
dorsal/ventral axis specification, ovarian follicular epithelium
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
intrinsic apoptotic signaling pathway in response to DNA damage
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
positive regulation of gene expression
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
nurse cell apoptotic process
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
TAS
positive regulation of nurse cell apoptotic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The E2F cell cycle regulator is required for Drosophila nurse cell DNA replication and apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
oogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
regulation of cell cycle
determination method
IMP
NAS
3 references
retrieved
16 July 2018
stated in
The genetic control of organ growth: insights from Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
NAS
retrieved
16 July 2018
stated in
Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IMP
retrieved
16 July 2018
stated in
A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24318&geneProductId=UniProtKB:Q24318
determination method
IMP
regulation of cell cycle
determination method
IEA
IMP
NAS
4 references
retrieved
8 April 2019
stated in
The genetic control of organ growth: insights from Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
NAS
retrieved
8 April 2019
stated in
A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
retrieved
8 April 2019
stated in
Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24318
determination method
IEA
has part(s)
Transcription factor DP, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
E2F/DP family, winged-helix DNA-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q24318
Identifiers
RefSeq protein ID
NP_001260949
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36461
NP_477039
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36461
NP_725267
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36461
UniProt protein ID
Q24318
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q24318
Ensembl protein ID
FBpp0086853
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086853
FBpp0086854
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086854
FBpp0305354
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0305354
Sitelinks
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