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(Q29817050)
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English
Partner of inscuteable Dmel_CG5692
Protein found in Drosophila melanogaster
pins-PA
pins
partner of inscutable
rapsynoid
CG5692 gene product from transcript CG5692-RA
partner of inscuteable
rapsinoid
CG5692-PA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VB22
part of
Tetratricopeptide-like helical domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VB22
Tetratricopeptide repeat-containing domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Tetratricopeptide repeat family
1 reference
based on heuristic
inferred from protein domain or family
GoLoco motif domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VB22
encoded by
pins
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VB22
molecular function
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IPI
retrieved
8 April 2019
stated in
Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IPI
retrieved
8 April 2019
stated in
Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IPI
protein domain specific binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IPI
GTPase regulator activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IEA
cell component
cell cortex
determination method
IDA
TAS
2 references
retrieved
8 April 2019
stated in
Asymmetric localization and function of cell-fate determinants: a fly's view
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
retrieved
8 April 2019
stated in
Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
apical part of cell
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
NAS
apical cortex
determination method
IDA
TAS
6 references
retrieved
8 April 2019
stated in
Protein localization during asymmetric cell division
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
retrieved
8 April 2019
stated in
Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
retrieved
8 April 2019
stated in
Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
retrieved
8 April 2019
stated in
Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
retrieved
8 April 2019
stated in
Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
retrieved
8 April 2019
stated in
Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
biological process
establishment of mitotic spindle orientation
determination method
IDA
IMP
3 references
retrieved
8 April 2019
stated in
A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
retrieved
8 April 2019
stated in
The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
retrieved
8 April 2019
stated in
Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
neuroblast fate determination
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
neuroblast proliferation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
asymmetric cell division
determination method
IDA
IMP
TAS
4 references
retrieved
8 April 2019
stated in
Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
retrieved
8 April 2019
stated in
Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
retrieved
8 April 2019
stated in
A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
retrieved
8 April 2019
stated in
The interphase microtubule aster is a determinant of asymmetric division orientation in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IDA
establishment of mitotic spindle localization
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
retrieved
8 April 2019
stated in
Mechanisms of spindle positioning: focus on flies and worms
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
asymmetric protein localization involved in cell fate determination
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Mechanisms of spindle positioning: focus on flies and worms
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
basal protein localization
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
TAS
maintenance of protein location
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Protein localization during asymmetric cell division
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
NAS
regulation of catalytic activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IEA
establishment of spindle orientation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
asymmetric neuroblast division
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
retrieved
8 April 2019
stated in
The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VB22
determination method
IMP
has part(s)
tetratricopeptide repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VB22
GoLoco motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VB22
Tetratricopeptide repeat-containing domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VB22
Identifiers
RefSeq protein ID
NP_524999
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
53569
UniProt protein ID
Q9VB22
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VB22
Ensembl protein ID
FBpp0084559
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0084559
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