(Q29817158)

English

Regulatory particle non-ATPase 10 Dmel_CG7619

Protein found in Drosophila melanogaster

CG7619 gene product from transcript CG7619-RA
54 kda mu particle subunit of 26S protease
CG7619-PB
proteasome 54kD subunit
Rpn10-PA
Rpn10
subunit S5a
Rpn10-PB
CG7619-PA
regulatory particle non-ATPase 10

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No description defined

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Statements

1 reference

25 May 2022

von Willebrand factor A-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P55035

von Willebrand factor, type A, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin interacting motif, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

3 references

8 April 2019

Overexpression of Dsk2/dUbqln results in severe developmental defects and lethality in Drosophila melanogaster that can be rescued by overexpression of the p54/Rpn10/S5a proteasomal subunit

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

Cost-effective strategies for completing the interactome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

UbcD4, a ubiquitin-conjugating enzyme in Drosophila melanogaster expressed in pole cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

1 reference

8 April 2019

Zn2+-induced reversible dissociation of subunit Rpn10/p54 of the Drosophila 26 S proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

IDA

ubiquitin conjugating enzyme binding

1 reference

8 April 2019

UbcD4, a ubiquitin-conjugating enzyme in Drosophila melanogaster expressed in pole cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

1 reference

1 January 2018

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

1 reference

1 January 2018

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

determination method

IDA

proteasome regulatory particle

4 references

8 April 2019

The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

Zn2+-induced reversible dissociation of subunit Rpn10/p54 of the Drosophila 26 S proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

1 reference

8 April 2019

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

HDA

biological process

mitotic sister chromatid segregation

1 reference

8 April 2019

Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

IMP

cellular response to DNA damage stimulus

1 reference

1 January 2018

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

TAS

Toll signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

TAS

proteasome-mediated ubiquitin-dependent protein catabolic process

4 references

1 January 2018

Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 January 2018

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 January 2018

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 January 2018

26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55035&geneProductId=UniProtKB:P55035

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

IBA

proteasome-mediated ubiquitin-dependent protein catabolic process

5 references

8 April 2019

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55035

determination method

IBA

has part(s)

von Willebrand factor, type A

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P55035

Ubiquitin interacting motif

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P55035

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

(Q29817158)

Regulatory particle non-ATPase 10 Dmel_CG7619

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