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(Q29817187)
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DJ-1alpha Dmel_CG6646
Protein found in Drosophila melanogaster
CG6646-PA
DJ-1alpha
DJ-1alpha-PA
CG6646 gene product from transcript CG6646-RA
DJ-1A
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9J4
part of
Protein/nucleic acid deglycase DJ-1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9J4
Class I glutamine amidotransferase-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9J4
DJ-1/PfpI domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9J4
encoded by
DJ-1alpha
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9J4
molecular function
protein deglycase activity
determination method
ISS
1 reference
retrieved
27 March 2018
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4
determination method
ISS
protein deglycase activity
determination method
IBA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
ISS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IBA
oxidoreductase activity, acting on peroxide as acceptor
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
ISS
cell component
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4
determination method
IEA
mitochondrion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IEA
nucleus
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IBA
cytosol
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IBA
biological process
response to oxidative stress
determination method
IDA
IMP
3 references
retrieved
8 April 2019
stated in
Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IMP
retrieved
8 April 2019
stated in
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IDA
phosphatidylinositol 3-kinase signaling
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IGI
dopamine metabolic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IMP
mitochondrial ATP synthesis coupled electron transport
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IGI
regulation of protein kinase B signaling
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IMP
retrieved
8 April 2019
stated in
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IGI
neuron cellular homeostasis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IMP
protein deglycation
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4
determination method
IEA
protein deglycation, glyoxal removal
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IBA
guanine deglycation, glyoxal removal
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4
determination method
IBA
has part(s)
DJ-1/PfpI
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9J4
Identifiers
RefSeq protein ID
NP_610916
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36543
UniProt protein ID
A1Z9J4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9J4
Ensembl protein ID
FBpp0086741
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086741
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