(Q29817304)

English

Mutagen-sensitive 312 Dmel_CG8601

Protein found in Drosophila melanogaster

mus312
CG8601-PA
CG8601-PE
CG8601-PD
mus312-PD
mutagen-sensitive 312
mus312-PE
mus312-PA
CG8601 gene product from transcript CG8601-RE

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Statements

1 reference

25 May 2022

Structure-specific endonuclease subunit Slx4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9VS48

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

4 references

8 April 2019

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IPI

crossover junction endodeoxyribonuclease activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IBA

3'-flap endonuclease activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

2 references

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VS48&geneProductId=UniProtKB:Q9VS48

27 February 2018

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VS48&geneProductId=UniProtKB:Q9VS48

27 February 2018

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VS48&geneProductId=UniProtKB:Q9VS48

determination method

IDA

protein-containing complex

1 reference

8 April 2019

Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IBA

biological process

meiotic DNA double-strand break processing

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IBA

resolution of meiotic recombination intermediates

1 reference

27 February 2018

Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VS48&geneProductId=UniProtKB:Q9VS48

determination method

IMP

nucleotide-excision repair, DNA damage recognition

1 reference

8 April 2019

Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IEA

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IEA

reciprocal meiotic recombination

1 reference

8 April 2019

Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IMP

cell population proliferation

1 reference

8 April 2019

Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IGI

oocyte fate determination

1 reference

8 April 2019

Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IMP

homologous recombination

1 reference

8 April 2019

Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IGI

interstrand cross-link repair

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IBA

meiotic chromosome segregation

1 reference

8 April 2019

Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VS48

determination method

IMP

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

(Q29817304)

Mutagen-sensitive 312 Dmel_CG8601

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