(Q29817832)

English

Timeless Dmel_CG3234

Protein found in Drosophila melanogaster

CG3234-PT
CG3234-PL
tim-PB
timeless1
CG3234-PB
tim-PP
tim-PR
CG3234-PP
tim
tim-PM
CG3234-PM
tim-PL
tim-PS
tim-PT
CG3234 gene product from transcript CG3234-RR
tim-PO
tim-PN
CG3234-PS
timeless
CG3234-PR
CG3234-PN
CG3234-PO
dtimeless
ritsu

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Timeless protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

6 references

8 April 2019

Light-dependent sequestration of TIMELESS by CRYPTOCHROME

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

A role for the PERIOD:PERIOD homodimer in the Drosophila circadian clock.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Light-dependent sequestration of TIMELESS by CRYPTOCHROME

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Flavin reduction activates Drosophila cryptochrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

transcription factor binding

determination method

1 reference

8 April 2019

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

protein heterodimerization activity

determination method

3 references

8 April 2019

A rhythmic Ror.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

From biological clock to biological rhythms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

7 references

16 July 2018

Genetic analysis of the circadian system in Drosophila melanogaster and mammals

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

Novel insights into the regulation of the timeless protein.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

Impaired clock output by altered connectivity in the circadian network.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

16 July 2018

Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

6 references

8 April 2019

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Light-dependent sequestration of TIMELESS by CRYPTOCHROME

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Impaired clock output by altered connectivity in the circadian network.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Novel insights into the regulation of the timeless protein.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

protein-containing complex

determination method

1 reference

8 April 2019

Light-dependent sequestration of TIMELESS by CRYPTOCHROME

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

nuclear chromosome

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49021&geneProductId=UniProtKB:P49021

determination method

determination method

8 references

8 April 2019

Genetic analysis of the circadian system in Drosophila melanogaster and mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Impaired clock output by altered connectivity in the circadian network.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Novel insights into the regulation of the timeless protein.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

replication fork protection complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

biological process

negative regulation of transcription by RNA polymerase II

determination method

3 references

8 April 2019

From biological clock to biological rhythms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

circadian regulation of heart rate

determination method

1 reference

8 April 2019

Time-restricted feeding attenuates age-related cardiac decline in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

protein import into nucleus

determination method

1 reference

8 April 2019

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

mating behavior

determination method

1 reference

8 April 2019

Circadian rhythms of female mating activity governed by clock genes in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

Regulation of copulation duration by period and timeless in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

rhythmic behavior

determination method

1 reference

8 April 2019

Genetic analysis of the circadian system in Drosophila melanogaster and mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

circadian rhythm

determination method

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

From biological clock to biological rhythms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Drugs, flies, and videotape: the effects of ethanol and cocaine on Drosophila locomotion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

A rhythmic Ror.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Circadian rhythms from flies to human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Central and peripheral circadian oscillator mechanisms in flies and mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Drosophila: genetics meets behaviour.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

eclosion rhythm

determination method

3 references

8 April 2019

Genetic analysis of the circadian system in Drosophila melanogaster and mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Clock mechanisms in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Drosophila: genetics meets behaviour.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

Natural selection favors a newly derived timeless allele in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

Drosophila: genetics meets behaviour.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

regulation of protein import into nucleus

determination method

1 reference

8 April 2019

From biological clock to biological rhythms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

regulation of circadian sleep/wake cycle

determination method

1 reference

8 April 2019

A Drosophila model for age-associated changes in sleep:wake cycles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

regulation of circadian sleep/wake cycle, sleep

determination method

3 references

8 April 2019

Perchance to dream: solving the mystery of sleep through genetic analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Effects of light interruption on sleep and viability of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Stress response genes protect against lethal effects of sleep deprivation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

negative phototaxis

determination method

1 reference

8 April 2019

Behavioral dissection of Drosophila larval phototaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

rhythmic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

circadian behavior

determination method

1 reference

8 April 2019

Regulation of the cycling of timeless (tim) RNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

regulation of phagocytosis

determination method

1 reference

8 April 2019

The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

positive regulation of phagocytosis

determination method

1 reference

8 April 2019

The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

circadian temperature homeostasis

determination method

1 reference

8 April 2019

Circadian rhythm of temperature preference and its neural control in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

cellular response to light stimulus

determination method

1 reference

8 April 2019

Evidence that the TIM light response is relevant to light-induced phase shifts in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

negative regulation of transcription regulatory region DNA binding

determination method

1 reference

8 April 2019

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

DNA replication checkpoint signaling

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

entrainment of circadian clock

determination method

3 references

8 April 2019

From biological clock to biological rhythms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Temperature-dependent resetting of the molecular circadian oscillator in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

replication fork arrest

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

replication fork protection

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49021

determination method

Timeless protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49021

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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