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Multi drug resistance 65 Dmel_CG10181
Protein found in Drosophila melanogaster
CG10181 gene product from transcript CG10181-RA
P-glycoprotein65-Dm
CG10181-PA
multi drug resistance 65
multiple drug resistance 65
P-glycoprotein
Mdr65-PA
Mdr65
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q00748
part of
ATP-binding cassette transporter
1 reference
Transporter Classification Database ID
3.A.1.201.31
retrieved
2 October 2019
based on heuristic
hierarchical database ID heuristic
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q00748
encoded by
Mdr65
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q00748
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
ATP binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
ABC-type xenobiotic transporter activity
determination method
IDA
IEA
2 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
24 April 2018
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IDA
efflux transmembrane transporter activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
hydrolase activity
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IEA
ATPase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
ATPase-coupled transmembrane transporter activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IEA
ABC-type xenobiotic transporter activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
ATPase-coupled transmembrane transporter activity
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IBA
cell component
pleated septate junction
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
integral component of membrane
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00748&geneProductId=UniProtKB:Q00748
determination method
IEA
ATP-binding cassette (ABC) transporter complex
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
plasma membrane
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IBA
integral component of membrane
determination method
IBA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q00748
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IBA
biological process
xenobiotic transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
response to toxic substance
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEP
xenobiotic transport
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
transmembrane transport
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEA
establishment of glial blood-brain barrier
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IDA
renal tubular secretion
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IEP
response to insecticide
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Describing the role of Drosophila melanogaster ABC transporters in insecticide biology using CRISPR-Cas9 knockouts.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00748
determination method
IMP
Identifiers
RefSeq protein ID
NP_476831
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
38726
UniProt protein ID
Q00748
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q00748
Ensembl protein ID
FBpp0076719
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0076719
Transporter Classification Database ID
3.A.1.201.31
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
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