(Q29818583)

English

Haywire Dmel_CG8019

Protein found in Drosophila melanogaster

hay
CG8019-PA
hay-PA
haywire
CG8019-PB
CG8019 gene product from transcript CG8019-RA
hay-PB

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Helicase XPB/Ssl2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase/UvrB, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase XPB/Ssl2, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ERCC3/RAD25/XPB helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

DNA helicase activity

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

helicase activity

determination method

4 references

1 January 2018

A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

The drosophila melanogaster genome: translation factors and RNA binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

protein binding

determination method

1 reference

1 January 2018

Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

3'-5' DNA helicase activity

determination method

1 reference

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

determination method

5 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Purification of the Drosophila RNA polymerase II general transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Identification of alternative splicing regulators by RNA interference in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

transcription factor TFIIH holo complex

determination method

4 references

1 January 2018

Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Purification of the Drosophila RNA polymerase II general transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

biological process

regulation of alternative mRNA splicing, via spliceosome

determination method

1 reference

1 January 2018

Identification of alternative splicing regulators by RNA interference in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

promoter clearance from RNA polymerase II promoter

determination method

1 reference

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

transcription open complex formation at RNA polymerase II promoter

determination method

1 reference

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

nucleotide-excision repair

determination method

3 references

1 January 2018

A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

regulation of transcription, DNA-templated

determination method

1 reference

1 January 2018

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

transcription by RNA polymerase II

determination method

1 reference

1 January 2018

RNA polymerase II 140wimp mutant and mutations in the TFIIH subunit XPB differentially affect homeotic gene expression in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

cellular response to DNA damage stimulus

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

determination method

1 reference

1 January 2018

A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

DNA duplex unwinding

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

regulation of growth

determination method

1 reference

1 January 2018

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

regulation of cell population proliferation

determination method

1 reference

1 January 2018

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

regulation of RNA polymerase II regulatory region sequence-specific DNA binding

determination method

1 reference

1 January 2018

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02870&geneProductId=UniProtKB:Q02870

determination method

Helicase XPB/Ssl2, N-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Helicase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Helicase/UvrB, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Helicase superfamily 1/2, ATP-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

ERCC3/RAD25/XPB helicase, C-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02870

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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