(Q29818771)

English

Easter Dmel_CG4920

Protein found in Drosophila melanogaster

CG4920 gene product from transcript CG4920-RB
easter
ea
ea-PA
CG4920-PB
CG4920-PA
ea-PB

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

peptidase S1A, chymotrypsin family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13582

Peptidase S1, PA clan

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13582

Proteinase, regulatory CLIP domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13582

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proteinase, regulatory CLIP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, serine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

endopeptidase activity

determination method

1 reference

10 September 2018

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

serine-type endopeptidase activity

determination method

4 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

serine-type peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

serine-type endopeptidase activity

determination method

5 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

serine-type endopeptidase activity

determination method

11 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

A ventrally localized protease in the Drosophila egg controls embryo dorsoventral polarity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

In vitro maturation of Drosophila melanogaster Spätzle protein with refolded Easter reveals a novel cleavage site within the prodomain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Spatial regulation of developmental signaling by a serpin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

serine-type endopeptidase activity

determination method

11 references

8 April 2019

Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A ventrally localized protease in the Drosophila egg controls embryo dorsoventral polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

In vitro maturation of Drosophila melanogaster Spätzle protein with refolded Easter reveals a novel cleavage site within the prodomain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Spatial regulation of developmental signaling by a serpin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

perivitelline space

determination method

1 reference

8 April 2019

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

extracellular space

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

biological process

determination method

4 references

27 February 2018

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

27 February 2018

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

maternal specification of dorsal/ventral axis, oocyte, germ-line encoded

determination method

1 reference

8 April 2019

The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

ventral furrow formation

determination method

1 reference

8 April 2019

Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sites

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

Toll signaling pathway

determination method

dorsal/ventral axis specification

determination method

3 references

10 September 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

The antimicrobial host defense of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

10 September 2018

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13582&geneProductId=UniProtKB:P13582

determination method

dorsal/ventral pattern formation

determination method

1 reference

8 April 2019

Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sites

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

determination method

7 references

8 April 2019

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A ventrally localized protease in the Drosophila egg controls embryo dorsoventral polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

Toll signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

dorsal/ventral axis specification

determination method

7 references

8 April 2019

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

The role of easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Positive and negative regulation of Easter, a member of the serine protease family that controls dorsal-ventral patterning in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A serpin regulates dorsal-ventral axis formation in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

positive regulation of Toll signaling pathway

determination method

7 references

8 April 2019

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Positive and negative regulation of Easter, a member of the serine protease family that controls dorsal-ventral patterning in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Spatial regulation of developmental signaling by a serpin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

A serpin regulates dorsal-ventral axis formation in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Activation of a protease cascade involved in patterning the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

8 April 2019

Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13582

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Multilingual sites(0 entries)

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